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Hypothyroidism decreases proinsulin gene expression and the attachment of its mRNA and eEF1A protein to the actin cytoskeleton of INS-1E cells
(Associação Brasileira de Divulgação Científica, 2011)
The actions of thyroid hormone (TH) on pancreatic beta cells have not been thoroughly explored, with current knowledge being limited to the modulation of insulin secretion in response to glucose, and beta cell viability ...
Human erythrocytes: cytoskeleton and its origin
(Springer, 2020-05)
In the last few years, erythrocytes have emerged as the main determinant of blood rheology. In mammals, these cells are devoid of nuclei and are, therefore, unable to divide. Consequently, all circulating erythrocytes come ...
Neuronal protein trafficking: Emerging consequences of endoplasmic reticulum dynamics
(2011)
The highly polarized morphology and complex geometry of neurons is determined to a great extent by the structural and functional organization of the secretory pathway. It is intuitive to propose that the spatial arrangement ...
Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport
(2007)
The cytoskeleton and cytoskeletal motors play a fundamental role in neurotransmitter receptor trafficking, but proteins that link GABAB receptors (GABABRs) to the cytoskeleton have not been described. We recently identified ...
Wnt5a Signaling in Gastric Cancer
(Frontiers Media S.A., 2020)
The role of cytoskeleton and adhesion proteins in the resistance to photodynamic therapy: possible therapeutic interventions
(Royal Society of Chemistry, 2015-04)
It is known that Photodynamic Therapy (PDT) induces changes in the cytoskeleton, the cell shape, and the adhesion properties of tumour cells. In addition, these targets have also been demonstrated to be involved in the ...
Subpopulations of tau interact with microtubules and actin filaments in various cell types
(1995)
It has been demonstrated that microtubule‐associated proteins (MAPs) interact with tubulin in vitro and in vivo. However, there is no clear evidence on the possible roles of the interactions of MAPs in vivo with other ...
Management of cytoskeleton architecture by molecular chaperones and immunophilins
(Elsevier Science Inc, 2011-12)
Cytoskeletal structure is continually remodeled to accommodate normal cell growth and to respond to pathophysiological cues. As a consequence, several cytoskeleton-interacting proteins become involved in a variety of ...
IRE1 alpha governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
(2018)
Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer ...