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Mechanisms underlying the inhibition of the cytochrome P450 system by copper ions
(2009)
Copper toxicity has been associated to the capacity of free copper ions to catalyze the production of superoxide anion and hydroxyl radical, reactive species that modify the structure and/or function of biomolecules. In ...
Redox dysregulation and bioaccumulation of copper in tilapia Oreocromis niloticus
(Wiley-Blackwell, 2014-03-01)
The objective of this study was to evaluate the effect of two concentrations of copper (0.13 and 0.5mgL(-1)) on juveniles of tilapia, Oreocromis niloticus (Linnaeus), using two toxicological assays (I- copper exposure and ...
Mechanisms underlying the inhibition of the cytochrome P450 system by copper ions
(WILEY, 2009)
Copper toxicity has been associated to the capacity of free copper ions to catalyze the production of superoxide anion and hydroxyl radical, reactive species that modify the structure and/or function of biomolecules. In ...
Limits of metabolic tolerance to copper and biological basis for present recommendations and regulations
(American Society for Nutrition, 1996)
Acute copper toxicity is infrequent in humans. The evidence for chronic toxicity is derived principally from patients with Wilson disease and cases of infantile cirrhosis that were related to excessive copper intakes. The ...
Ternary copper(II) complex of 5-hydroxytryptophan and 1,10-phenanthroline with several pharmacological properties and an adequate safety profile
(Elsevier Science Inc, 2019-12)
We report the synthesis and biological evaluation of a ternary copper complex, [Cu(5HTP)(phen)(H2O)](NO3).2H2O, with the antioxidant agent 5-hydroxytryptophan (5-HTP) and phenanthroline (phen, added to improve its lipophilicity ...