Buscar
Mostrando ítems 1-10 de 180
Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioning
(Cold Spring Harbor Lab Press, 2013-10)
The present research investigated the resulting contextual fear memory and structural plasticity changes in the dorsal hippocampus (DH) following stress and fear conditioning. This combination enhanced fear retention and ...
Disruptive effect of midazolam on fear memory reconsolidation: Decisive influence of reactivation time span and memory age
(Nature Publishing Group, 2009-01)
Benzodiazepine (BDZ) administered shortly after retrieval disrupts the reconsolidation of fear memory. In this research, we explored the way in which different factors that limit the emergence of such process may affect ...
Contextual, but not auditory, fear conditioning is disrupted by neurotoxic selective lesion of the basal nucleus of amygdala in rats
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
The basolateral amygdala complex (BLA) is involved in acquisition of contextual and auditory fear conditioning. However, the BLA is not a single structure but comprises a group of nuclei, including the lateral (LA), basal ...
Prior stress promotes the generalization of contextual fear memories: Involvement of the gabaergic signaling within the basolateral amygdala complex
(Pergamon-Elsevier Science Ltd, 2018-04)
Fear generalization occurs when a response, previously acquired with a threatening stimulus, is transferred to a similar one. However, it could be maladaptive when stimuli that do not represent a real threat are appraised ...
Dorsolateral periaqueductal gray stimulation prior to retrieval potentiates a contextual fear memory in rats
(Elsevier Science, 2012-09)
The association of a neutral context with an aversive stimulus, such as foot-shock, result in a contextual fear memory. A growing number of evidence have revealed that prior exposure to diverse threatening situations ...
Effects of pre- or post-training entorhinal cortex AP5 injection on fear conditioning
(Elsevier B.V., 2005-11-15)
Fear conditioning is one of the most studied paradigms to assess the neural basis of emotional memory. the circuitry involves NNMA receptor activation in the amygdala and, in the case of contextual conditioning, in the ...
Involvement of the prelimbic cortex in contextual fear conditioning with temporal and spatial discontinuity
(Academic Press Inc Elsevier Science, 2017)
Time plays an important role in conditioning, it is not only possible to associate stimuli with events that overlap, as in delay fear conditioning, but it is also possible to associate stimuli that are discontinuous in ...
Reactivation-Dependent Amnesia for Contextual Fear Memories: Evidence for Publication Bias
(Society for Neuroscience, 2020-12)
Research on memory reconsolidation has been booming in the last two decades, with numerous high-impact publications reporting promising amnestic interventions in rodents and humans. However, our own recently-published ...
Post-weaning housing conditions influence freezing during contextual fear conditioning in adult rats
(Elsevier Science, 2018-11)
The present study aimed to investigate the influence of housing conditions on contextual fear memory malleability. Male Wistar rats were housed in enriched, standard, or impoverished conditions after weaning and remained ...
What ethologically based models have taught us about the neural systems underlying fear and anxiety
(Associação Brasileira de Divulgação Científica, 2012)
Classical Pavlovian fear conditioning to painful stimuli has provided the generally accepted view of a core system centered in the central amygdala to organize fear responses. Ethologically based models using other sources ...