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The Footprint of Polygenic Adaptation on Stress-Responsive Cis-Regulatory Divergence in the Arabidopsis Genus
(Oxford University Press, 2016-08)
Adaptation of a complex trait often requires the accumulation of many modifications to finely tune its underpinning molecular components to novel environmental requirements. The investigation of cis-acting regulatory ...
Functionally conserved cis-regulatory elements of COL18A1 identified through zebrafish transgenesis
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
Type XVIII collagen is a component of basement membranes, and expressed prominently in the eye, blood vessels, liver, and the central nervous system. Homozygous mutations in COL18A1 lead to Knobloch Syndrome, characterized ...
In silico identification of cis-regulatory elements in folate biosynthesis and 1C metabolism genes in plants
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-11-26)
Folates (vitamin B9) are enzyme cofactors required for all organisms for one-carbon (1C) transfer reactions. A deficiency of these nutrients can lead to several health problems. Since humans are not natural producers of ...
Cracking the genome's second code: Enhancer detection by combined phylogenetic footprinting and transgenic fish and frog embryos
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-07)
Genes involved in vertebrate development are unusually enriched for highly conserved non-coding sequence elements. These regions are readily detected in silico, by genome-wide sequence comparisons between different ...
Cracking the genome's second code: Enhancer detection by combined phylogenetic footprinting and transgenic fish and frog embryos
(2006)
Genes involved in vertebrate development are unusually enriched for highly conserved non-coding sequence elements. These regions are readily detected in silico, by genome-wide sequence comparisons between different ...
Gestão econômica e financeira de consórcios intermunicipais de saúde no Rio Grande do Sul
(Universidade do Vale do Rio dos Sinos, 2015-07-27)
The objective of this study is to analyze the use of economic and financial management practices used by public health consortiums (CIS) established in Rio Grande do Sul. The CIS are regional and intergovernmental cooperation ...
Gestão econômica e financeira de consórcios intermunicipais de saúde no Rio Grande do Sul
(Universidade do Vale do Rio dos Sinos, 2015-07-27)
The objective of this study is to analyze the use of economic and financial management practices used by public health consortiums (CIS) established in Rio Grande do Sul. The CIS are regional and intergovernmental cooperation ...
Commentary: Systems biology approach to model the life cycle of Trypanosoma cruzi
(Frontiers Research Foundation, 2017-01)
In a recent work we have identified, from a bigger gene regulatory network, a seven-node moduleinvolved in the control of the life cycle of Trypanosoma cruzi (T. cruzi) (Carrea and Diambra,2016). To that end, we have ...