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Chronic use of marijuana decreases cannabinoid receptor binding and mRNA expression in the human brain
(Elsevier B.V., 2007-03-02)
Chronic exposure to Cannabis sativa (marijuana) produced a significant down-regulation of cannabinoid receptor in the postmortem human brain. the significant decrease in maximal binding capacity was not accompanied by ...
Ethopharmacological evaluation of the rat exposure test: A prey-predator interaction test
(2013-03-01)
The rat exposure test (RET) is a prey (mouse)-predator (rat) situation that activates brain defensive areas and elicits hormonal and defensive behavior in the mouse. Here, we investigated possible correlations between the ...
Ethopharmacological evaluation of the rat exposure test: A prey-predator interaction test
(2013-03-01)
The rat exposure test (RET) is a prey (mouse)-predator (rat) situation that activates brain defensive areas and elicits hormonal and defensive behavior in the mouse. Here, we investigated possible correlations between the ...
Stress Abolishes the Effect of Previous Chronic Ethanol Consumption on Drug Place Preference and on the Mesocorticolimbic Brain Pathway
(Wiley-Blackwell, 2014-05-01)
BackgroundConditioned place preference (CPP) to ethanol (EtOH) is an important addiction-related alteration thought to be mediated by changed neurotransmission in the mesocorticolimbic brain pathway. Stress is a factor of ...
Perinatal exposure to parasiticide ivermectin: Long-term effects on reproductive parameters of adult male rats
(2011-02-01)
Ivermectin is one of the most widely used antiparasitic drugs globally. The aim of this study was to evaluate the chronic effects of perinatal exposure to ivermectin on male reproductive parameters in rats. Pregnant rats ...
Exposure to chronic stress increases the locomotor response to cocaine and the basal levels of corticosterone in adolescent rats
(Taylor & Francis Ltd, 2005-09-01)
Repeated exposure to stress results in augmentation in the locomotor response to psychostimulant drugs. We investigated the locomotor response to a novel environment or cocaine [ 10 mg/kg, intraperitoneally (i.p.)] and ...
Exposure to chronic stress increases the locomotor response to cocaine and the basal levels of corticosterone in adolescent rats
(Taylor & Francis Ltd, 2005-09-01)
Repeated exposure to stress results in augmentation in the locomotor response to psychostimulant drugs. We investigated the locomotor response to a novel environment or cocaine [ 10 mg/kg, intraperitoneally (i.p.)] and ...
Rational Pharmacotherapy in Infectious Diseases: Issues Related to Drug Residues in Edible Animal Tissues
(Multidisciplinary Digital Publishing Institute, 2021-10)
Drugs are used in veterinary medicine to prevent or treat animal diseases. When rationally administered to livestock following Good Veterinary Practices (GVP), they greatly contribute to improving the production of food ...