Now showing items 1-10 of 107
Oxidation of amino acids by chlorpromazine cation radical and co-catalysis by chlorpromazine
The long-tem use of chlorpromazine (CPZ) may cause severe side effects. This property of CPZ might be related to pro-oxidant effects of the chlorpromazine cation radical (CPZ•+), which can be easily generated by catalytic ...
Interactions of chlorpromazine with phospholipid monolayers: Effects of the ionization state of the drug
(Elsevier Science BvAmsterdamHolanda, 2007)
Chlorpromazine quantification in human plasma by UPLC-electrospray ionization tandem mass spectrometry. Application to a comparative pharmacokinetic study
(Elsevier Science BvAmsterdamHolanda, 2011)
The co-catalytic effect of chlorpromazine on peroxidase-mediated oxidation of melatonin: enhanced production of N-1-acetyl-N (2)-formyl-5-methoxykynuramine
(Blackwell Publishing, 2008-03-01)
Accumulating evidence points to relationships between increased production of reactive oxygen or decreased antioxidant protection in schizophrenic patients. Chlorpromazine (CPZ), which remains a benchmark treatment for ...