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Mechanistic insights into the pathogenesis of microtubule‐targeting agent‐induced peripheral neuropathy from pharmacogenetic and functional studies
(Wiley Blackwell Publishing, Inc, 2022-01)
Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting toxicity that affects 30%-40% of patients undergoing cancer treatment. Although multiple mechanisms of chemotherapy-induced neurotoxicity have ...
Anti-allodynic and anti-inflammatory effects of 17alpha-hydroxyprogesterone caproate in oxaliplatin-induced peripheral neuropathy
(Wiley Blackwell Publishing, Inc, 2019-01)
Chemotherapy-induced peripheral neuropathy is a disabling condition induced by several frequently used chemotherapeutic drugs including the front-line agent oxaliplatin. Symptoms are predominantly sensory with the development ...
Effects of exercise interventions to reduce chemotherapy-induced peripheral neuropathy severity: A meta-analysis
(John Wiley and Sons Inc, 2024)
Impact of Adjuvant FOLFOX on Quality of Life and Peripheral Neuropathy Incidence in Patients With Gastric Cancer: A Prospective Cohort Study
(Elsevier Inc., 2023)
Objectives: Perioperative and adjuvant chemotherapy have demonstrated clinical benefits in localized gastric cancer. Nevertheless, the reports on their effects on patient's health-related quality of life (HRQoL) are scarce. ...
O uso de substâncias antioxidantes no tratamento de neuropatia periférica induzida por quimioterapia em modelos experimentaisThe use of antioxidant agents for chemotherapy-induced peripheral neuropathy treatment in animal models
(Pós-Graduação em Ciências da SaúdeUniversidade Federal de Sergipe, 2017)
Metformin protects from oxaliplatin induced peripheral neuropathy in rats
(Elsevier BV, 2020-08)
Oxaliplatin is a commonly used drug to treat cancer, extending the rate of disease-free survival by 20% in colorectal cancer. However, oxaliplatin induces a disabling form of neuropathy resulting in more than 60% of patients ...
Neuropatia periférica induzida por quimioterapia: uma revisão integrativa da literatura
(Universidade Federal de Santa MariaBrasilCiências da SaúdeUFSMPrograma de Pós-Graduação em Ciências da SaúdeCentro de Ciências da Saúde, 2021-08-24)
Antineoplastic chemotherapy represents the use of isolated or combined chemical substances in the treatment of malignant tumors, being considered one of the most important ways to fight cancer. Peripheral neuropathy (PN) ...
Potencialização da síndrome dolorosa induzida por paclitaxel pela inibição da enzima conversora de angiotensina e o envolvimento das cininas
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2016-02-23)
Paclitaxel is a chemotherapeutic agent widely used in the treatment of solid tumors. However, it causes adverse effects that limit their use, such as acute pain syndrome and peripheral sensory neuropathy. These sensory ...
Neuropatia periférica induzida por quimioterapia e sua associação com quedas e síndrome das pernas inquietasPeripheral neuropathy induced by chemotherapy and its association with falls and restless legs syndrome
(Pós-Graduação em Ciências da SaúdeUniversidade Federal de Sergipe, 2018)