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Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs
(2009)
BACKGROUND. Multidrug resistance (MDR) proteins have been associated with the lack of chemotherapy response. Expression of these proteins has been described in the prostate, but there is no information about their role in ...
Effect of chemotherapeutic drugs on telomere length and telomerase activity
(Smart Science & Technology, 2016-12)
Telomeres are specialized nucleoproteic complexes localized at the ends of eukaryotic chromosomes, that maintain their stability and integrity. They protect chromosome ends from fusion and from being recognized as sites ...
The influence of fixed and free final time of treatment on optimal chemotherapeutic protocols
(Pergamon-elsevier Science LtdOxfordInglaterra, 1998)
Acyl-CoA synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression
(Pergamon-Elsevier Science Ltd, 2019-01)
Acyl-CoA synthetase-4 (ACSL4) is an enzyme implicated in estrogen receptor α (ERα) negative regulation and hormone therapy resistance in breast cancer. In addition, ACSL4 has been associated to certain types of hormone ...
New insights towards mesoporous silica nanoparticles as a technological platform for chemotherapeutic drugs delivery
(2019-06-10)
Mesoporous silica nanoparticles (MSNs)displays interesting properties for biomedical applications such as high chemical stability, large surface area and tunable pores diameters and volumes, allowing the incorporation of ...
Combinatorial effects of geopropolis produced by Melipona fasciculata Smith with anticancer drugs against human laryngeal epidermoid carcinoma (HEp-2) cells
(2016-07-01)
The identification of natural products exerting a combined effect with therapeutic agents could be an alternative for cancer treatment, reducing the concentration of the drugs and side effects. Geopropolis (Geo) is produced ...