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Nitric oxide is not involved in Neisseria gonorrhoeae-induced cellular damage of human Fallopian tubes in vitro
(Sociedad de Biología de Chile, 2010)
The role of mitochondrial DNA damage in the citotoxicity of reactive oxygen species
(SPRINGER/PLENUM PUBLISHERS, 2011)
Mitochondria contain their own genome, a small circular molecule of around 16.5 kbases. The mitochondrial DNA (mtDNA) encodes for only 13 polypeptides, but its integrity is essential for mitochondrial function, as all 13 ...
Vitamin E supplementation inhibits muscle damage and inflammation after moderate exercise in hypoxia
(Wiley-Blackwell, 2016-08-01)
BackgroundExercise under hypoxic conditions represents an additional stress in relation to exercise in normoxia. Hypoxia induces oxidative stress and inflammation as mediated through tumour necrosis factor (TNF)- release ...
Intra- and extra-cellular DNA damage by harmine and 9-methyl-harmine
(Elsevier, 2014-01)
It is known that β-carbolines are able to produce photosensitized damage in cell-free DNA, but there is little information on their effects on cellular DNA. Therefore, we have analyzed the DNA damage produced by harmine ...
Krüppel-like Factor 6 is required for oxidative and oncogene-induced cellular senescence
(Frontiers Media S.A., 2019-11)
Krüppel-like factor 6 (KLF6) is a transcription factor involved in the regulation of several cellular processes. Regarding its role in tumorigenesis, KLF6 is considered a tumor suppressor. Numerous reports demonstrate its ...
Krüppel-like factor 6 Is required for oxidative and oncogene-iduced cellular senescence
(Frontiers Media S.A., 2019-11)
Krüppel-like factor 6 (KLF6) is a transcription factor involved in the regulation of several cellular processes. Regarding its role in tumorigenesis, KLF6 is considered a tumor suppressor. Numerous reports demonstrate its ...