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Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?
(Frontiers Media, 2020-08)
G-protein–coupled receptors (GPCRs) are targets for around one third of currently approved and clinical prescribed drugs and represent the largest and most structurally diverse family of transmembrane signaling proteins, ...
Innate immune cells' contribution to systemic lupus erythematosus
(Frontiers Media S.A., 2019)
ANGIOTENSINERGIC AND CHOLINERGIC RECEPTORS OF THE SUBFORNICAL ORGAN MEDIATE SODIUM INTAKE INDUCED BY GABAergic ACTIVATION OF THE LATERAL PARABRACHIAL NUCLEUS
(Elsevier B.V., 2014-03-14)
Bilateral injections of the GABA(A) agonist muscimol into the lateral parabrachial nucleus (LPBN) induce 0.3 M NaCl and water intake in satiated and normovolemic rats, a response reduced by intracerebroventricular (icv) ...
THE RETINAL TARGETS OF CENTRIFUGAL NEURONS AND THE RETINAL NEURONS PROJECTING TO THE ACCESSORY OPTIC-SYSTEM
(Cambridge Univ Press, 1994-03-01)
In birds, neurons of the isthmo-optic nucleus (ION), as well as ''ectopic'' neurons, send axons to the retina, where they synapse on cells in the inner nuclear layer (INL). Previous work has shown that centrifugal axons ...
Evidence for NL1-independent nuclear translocation of the mineralocorticoid receptor
(American Chemical Society, 2007)
In the absence of hormone, corticosteroid receptors are primarily located in the cytoplasm, and they rapidly accumulate in the nucleus (t0.5 = 5 min) upon ligand binding. It is generally believed that the dissociation of ...
The insulin receptor translocates to the nucleus to regulate cell proliferation in liver
(Williams & Wilkin, 2015)