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The role of the gene CCR5 polymorphisms CCR5 Delta 32 e CCR5 59029 in ocular toxoplasmosis.
(Elsevier B.V., 2018-08-01)
The Dual Role of CCR5 in the Course of Influenza Infection: Exploring Treatment Opportunities
(Frontiers Media, 2022)
Better CD4+T Cell Recovery in Brazilian HIV-Infected Individuals Under HAART Due to Cumulative Carriage of SDF-1-3`A, CCR2-V64I, CCR5-D32 and CCR5-Promoter 59029A/G Polymorphisms
(BENTHAM SCIENCE PUBL LTD, 2008)
Polymorphisms of chemokines and chemokine-receptors genes have been shown to influence the rate of progression to AIDS; however, their influence on response to HAART remains unclear. We investigated the frequency of the ...
Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population
(Brazilian Society of Infectious Diseases, 2003-08-01)
Entry of human immunodeficiency type 1 virus (HIV-1) into target cells requires both CD4and one of the chemokine receptors. Viruses predominantly use one, or occasionally both, of the major co-receptors CCR5 and CXCR4, ...
Avaliação da mutação ccr532 do receptor da quimiocina como marcador genético-histórico na população de Triunfo Pernambuco
(Universidade Federal de Pernambuco, 2014)
Distribution of the CCR5delta32 allele (gene variant CCR5) in Rondonia, Western Amazonian region, Brazil
(SOC BRASIL GENETICARIBEIRAO PRET, 2012)
Since around 1723, on the occasion of its initial colonization by Europeans, Rondonia has received successive waves of immigrants. This has been further swelled by individuals from northeastern Brazil, who began entering ...
CCR5 genotype and plasma ß-chemokine concentration of Brazilian HIV-infected individuals
(Associação Brasileira de Divulgação Científica (ABRADIC), 2002-11-01)
The 32-bp deletion in the HIV-1 co-receptor CCR5 confers a high degree of resistance to HIV-1 infection in homozygous individuals for the deleted allele and partial protection against HIV-1 during disease progression in ...
CCR5 genotype and plasma ß-chemokine concentration of Brazilian HIV-infected individuals
(Associação Brasileira de Divulgação Científica (ABRADIC), 2002-11-01)
The 32-bp deletion in the HIV-1 co-receptor CCR5 confers a high degree of resistance to HIV-1 infection in homozygous individuals for the deleted allele and partial protection against HIV-1 during disease progression in ...
Influence of NKG2C gene deletion and CCR5Δ32 in Pre-eclampsia—Approaching the effect of innate immune gene variants in pregnancy
(2019-04-01)
Pre-eclampsia (PE) is a hypertensive disorder that affects an important number of pregnant women worldwide. The exact causes of PE remain poorly understood. However, inflammation and deregulation of innate immune cells, ...
CCR5 chemokine receptor gene polymorphisms in ocular toxoplasmosis
(2018-02-01)
C–C chemokine receptor type 5 (CCR5) is a chemokine receptor that influences the immune response to infectious and parasitic diseases. This study aimed to determine whether the CCR5Δ32 and CCR5 59029 A/G polymorphisms are ...