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Prevalence and impact of founder mutations in hereditary breast cancer in Latin America
(Sociedade Brasileira de Genética, 2015)
Interactions between genetic predisposition and environmental toxicants for development of lung cancer
(Wiley-Blackwell, 1997-01-01)
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However. ...
Interactions between genetic predisposition and environmental toxicants for development of lung cancer
(Wiley-Blackwell, 1997-01-01)
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However. ...
Interactions between genetic predisposition and environmental toxicants for development of lung cancer
(1997-10-25)
Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However, ...
Germline variants in DNA repair genes are associated with young-onset head and neck cancer
(2021-11-01)
The genetic predisposition to head and neck carcinomas (HNSCC) and how the known risk factors (papillomavirus infection, alcohol, and tobacco consumption) contribute to the early-onset disease are barely explored. Although ...
Identification of predisposition genes involved in thyroid and breast carcinomas in patients with family history of these tumors by whole exome sequencing
(Amer Assoc Cancer Research, 2015-08-01)
Germline variants in driver genes of breast cancer and their association with familial and early-onset breast cancer risk in a chilean population
(MDPI, 2020)
The genetic variations responsible for tumorigenesis are called driver mutations. In breast cancer (BC), two studies have demonstrated that germline mutations in driver genes linked to sporadic tumors may also influence ...