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Role of natural killer cells in antitumor resistance
(2005-12-01)
Natural killer cells constitute a population of lymphocytes able to non-specifically destroy virus-infected and some kinds of tumor cells. Since this lytic activity was shown by non-immunized animals the phenomenon is ...
Physangulidine A, a withanolide from Physalis angulata, perturbs the cell cycle and induces cell death by apoptosis in prostate cancer cells
(American Chemical Society, 2013)
Recently, our group reported the discovery of three new withanolides, physangulidines A–C, from Physalis angulata. In this study, the biological effects of physangulidine A (1), which was the most active and abundant of ...
Targeting cancer stem cells with monoclonal antibodies: a new perspective in cancer therapy and diagnosis
(Expert Reviews, 2008-07-01)
This review discusses some of the impacts that biotechnology, genomics and nanotechnology convergence should have on future cancer management, in particular, the development of innovative diagnostic and therapeutic approaches ...
Evaluation of melatonin effect on human breast cancer stem cells using a threedimensional growth method of mammospheres
(2017-01-01)
Background: The high rates of women's death from breast cancer occur due to acquired resistance by patients to certain treatments, enabling the recurrence and/or tumor growth, invasion and metastasis. It has been demonstrated ...
Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells
(BioMed Central (BMC), 2022)
Bladder expression of CD cell surface antigens and cell-type-specific transcriptomes
(SPRINGERNEW YORK, 2013-08-02)
Many cell types have no known functional attributes. In the bladder and prostate, basal epithelial and stromal cells appear similar in cytomorphology and share several cell surface markers. Their total gene expression ...
Cancer stem cell genomics: the quest for early markers of malignant progression
(Expert Reviews, 2009-09-01)
Biologically distinct populations of neoplastic stem cells have been identified in a variety of human cancers, in which they are associated with the initial steps of tumorigenesis. the intrinsic properties of self-renewal, ...