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It's all about tau
(Elsevier Ltd, 2019)
Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer’s Disease
(Humana Press Inc., 2018)
Specific macromolecular interactions between tau and the microtubule system
(Kluwer Academic Publishers, 1992)
The microtubule-associated protein Tau, a major component of brain microtubules, shares common repeated C-terminal sequences with the high molecular-weight protein MAP-2. It has been shown that tau peptides V187-G204 and ...
Mechanisms of tau self-aggregation and neurotoxicity
(2011)
Pathological tau protein aggregates can be found in brain of patients with some of the neurodegenerative diseases collectively known as tauopathies, which include Alzheimer's disease (AD). Since tau post-translational ...
Subpopulations of tau interact with microtubules and actin filaments in various cell types
(1995)
It has been demonstrated that microtubule‐associated proteins (MAPs) interact with tubulin in vitro and in vivo. However, there is no clear evidence on the possible roles of the interactions of MAPs in vivo with other ...
Contribution of Tau pathology to mitochondrial impairment in neurodegeneration
(Frontiers Media S.A., 2018)
Inhibition of phospholipase A(2) in rat brain decreases the levels of total Tau protein
(SPRINGER WIEN, 2011)
The microtubule-associated protein Tau promotes the assembly and stability of microtubules in neuronal cells. Six Tau isoforms are expressed in adult human brain. All six isoforms become abnormally hyperphosphorylated and ...
Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons
(Academic Press Inc., 2014)