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Predicting binding modes of reversible peptide-based inhibitors of falcipain-2 consistent with structure-activity relationships
(Wiley-Blackwell, 2017-09-01)
Falcipain-2 ( FP-2) is a major hemoglobinase of Plasmodium falciparum, considered an important drug target for the development of antimalarials. A previous study reported a novel series of 20 reversible peptide-based ...
DNA interaction with hoechst 33258: stretching experiments decouple the different binding modes
(The Journal of Physical Chemistry B, 2018)
Prediction of the binding mode of N-2-phenylguanine derivative inhibitors to herpes simplex virus type 1 thymidine kinase
(Kluwer Academic PublDordrechtHolanda, 1998)
A new biophysics approach using photoacoustic spectroscopy to study the DNA-ethidium bromide interaction
(Springer, 2002-06-01)
We have examined the binding processes of ethidium bromide interacting with calf thymus DNA using photoacoustic spectroscopy. These binding processes are generally investigated by a combination of absorption or fluorescence ...
A new biophysics approach using photoacoustic spectroscopy to study the DNA-ethidium bromide interaction
(Springer, 2002-06-01)
We have examined the binding processes of ethidium bromide interacting with calf thymus DNA using photoacoustic spectroscopy. These binding processes are generally investigated by a combination of absorption or fluorescence ...
Structural modeling of high-affinity thyroid receptor-ligand complexes
(SPRINGER, 2010)
Understanding the molecular basis of the binding modes of natural and synthetic ligands to nuclear receptors is fundamental to our comprehension of the activation mechanism of this important class of hormone regulated ...
Structural modeling of high-affinity thyroid receptor-ligand complexes
(SpringerHeidelberg, 2010)
Understanding the molecular basis of the binding modes of natural and synthetic ligands to nuclear receptors is fundamental to our comprehension of the activation mechanism of this important class of hormone regulated ...
Plausible binding mode of the active α4β1 antagonist, MK-0617, determined by docking and free energy calculations
(World Scientific, 2012-12)
In the last years, the development of small molecule antagonists of VLA-4 for the treatment of diseases, where cell tra±cking and activation are important, has increased considerably. Among them, the MK-0617 ligand has ...