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Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience
(Elsevier B.V., 2007-01-01)
Background: the objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging. Methods: We included 14 consecutive patients with PD (9) or PSP (5). These measures included the ...
Clinical features of dystonia in atypical parkinsonism
(Academia Brasileira de Neurologia - ABNEURO, 2008-12-01)
BACKGROUND: The association between Dystonia and Parkinson's disease (PD) has been well described especially for foot and hand dystonia. There is however few data on dystonic postures in patients with atypical parkinsonism. ...
Fluency in Parkinson's disease: disease duration, cognitive status and age
(Academia Brasileira de Neurologia - ABNEURO, 2014-05-01)
The objective of this study was to determine the frequency of occurrence and to characterize the typology of dysfluencies in individuals with Parkinson’s disease (PD), including the variables age, gender, schooling, disease ...
Molecular Imaging Studies in Parkinson Disease Reducing Diagnostic Uncertainty
(Lippincott Williams & Wilkins, 2009-01-01)
Background: the diagnosis of Parkinson disease (PD) is based on clinical criteria but misdiagnosis is as high as 25% of cases as confirmed by anatomic-pathologic studies. Since the introduction of in vivo molecular imaging ...
Análise da fluência de fala na Doença de Parkinson
(Universidade Federal de São Paulo (UNIFESP), 2011-01-26)
Purpose: to characterize the frequency of occurrence and typology of disfluencies in individuals with PD verifying their relationship with the dysarthria and praxis verbal and nonverbal. Methods: This was a transversal ...
Progressive supranuclear palsy: new concepts
(Academia Brasileira de Neurologia - ABNEURO, 2010-12-01)
Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia. ...
Neurotoxicity Of Dietary Supplements From Annonaceae Species
(SAGE PUBLICATIONS INCTHOUSAND OAKS, 2015)
Mosaicism of alpha-synuclein gene rearrangements: Report of two unrelated cases of early-onset parkinsonism
(Elsevier, 2014-05)
In genetics, the term mosaicism describes the situation in which groups of cells have a different genetic composition to other cells in an organism. Somatic gene rearrangements due to multiplication or deletion of genes ...
ATP13A2 variants in early-onset Parkinson's disease patients and controls
(John Wiley and Sons Inc., 2009)
Four genes responsible for recessively inherited forms of Parkinson's disease (PD) have been identified, including the recently discovered ATP13A2 (PARK9) gene. Our objective was to investigate the role of this gene in a ...