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Genome-wide association study and heritability estimate for ectopic ureters in Entlebucher mountain dogs
(2018-12-01)
An ectopic ureter is a congenital anomaly which may lead to urinary incontinence and without a surgical intervention even to end-stage kidney disease. A genetic component contributes to the development of this anomaly in ...
Sustained reduction of healthcare-associated infections after the introduction of a bundle for prevention of ventilator-associated pneumonia in medical-surgical intensive care units
(2020-09-01)
Background: Infection control interventions can be erroneously interpreted if outcomes are assessed in short periods. Also, statistical methods usually applied to compare outcomes before and after interventions are not ...
Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes
(Lippincott Williams, 2009-05)
Purpose: We present an approach to prioritize single nucleotide polymorphisms for further follow-up in genome-wide association studies of type 2 diabetes. Method: The proposed method combines both the use of open data ...
Genome-wide association study of blood pressure extremes identifies variant near umod associated with hypertension
(PUBLIC LIBRAY OF SCIENCE, 2010)