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Perspectives for Novel Mixed Diruthenium-Organic Drugs as Metallopharmaceuticals in Cancer Therapy

SILVA, Denise de Oliveira (BENTHAM SCIENCE PUBL LTD, 2010)

Ruthenium compounds have been actively studied as metallodrugs for cancer therapy. Representatives of ruthenium-based antitumor drugs are the classes of ruthenium(III)-chlorido-(N-ligand)complexes, including the drugs ...

Vanadium, Ruthenium and Copper Compounds : A New Class of Nonplatinum Metallodrugs with Anticancer Activity

León, Ignacio Esteban; Cadavid Vargas, Juan Fernando; Di Virgilio, Ana Laura; Etcheverry, Susana Beatriz (2016)

Diruthenium(II, III) complexes of ibuprofen, aspirin, naproxen and indomethacin non-steroidal anti-inflammatory drugs: Synthesis, characterization and their effects on tumor-cell proliferation

RIBEIRO, Geise; BENADIBA, Marcel; COLQUHOUN, Alison; SILVA, Denise de Oliveira (PERGAMON-ELSEVIER SCIENCE LTD, 2008)

[Ru-2(dNSAID)(4)Cl] and novel [Ru-2(dNSAID)(4)(H2O)(2)]PF6 complexes, where dNSAID = deprotonated carboxylate from the non-steroidal anti-inflammatory drugs (NSIDs), respectively: ibuprofen, Hibp (1) and aspirin, Hasp (2); ...

Ru (II)–thyminate complexes new metallodrug candidates against tumor cells

Correa, Rodrigo de Souza; Freire, Vitória; Barbosa, Marília Imaculada Frazão; Bezerra, Daniel Pereira; Bomfim, Larissa M; Moreira, Diogo Rodrigo de Magalhães; Soares, Milena Botelho Pereira; Ellena, Javier Alcides; Batista, Alzir Azevedo (Royal Society of Chemistry, 2019)

Vanadium, Ruthenium and Copper Compounds: A New Class of Nonplatinum Metallodrugs with Anticancer Activity

Leon, Ignacio Esteban; Cadavid Vargas, Juan Fernando; Di Virgilio, Ana Laura; Etcheverry, Susana Beatriz (Bentham Science Publishers, 2017-01)

Cancer is a group of diseases involving abnormal cell growth. The cells grow uncontrollably with the potential to invade and spread to other parts of the body. This disease is one of the principal death causes in the world, ...

Functionalized nanoparticles as adjuvant to increase the cytotoxicity of metallodrugs toward tumor cells

Universidade de São Paulo (USP); Universidade Estadual Paulista (Unesp) (2019-01-07)

Functionalized MCM-41 is a class of new nanoporous biomaterials extensively studied as drug carriers of a diversity of therapeutic agents due to its suitable properties. In the present study, two oxindolimine complexes ...

Estudo pré-clínico de complexos de ouro (Au) como metalofármacos antileishmania e antitumoral

Tunes, Luiza Guimarães (2019)

Finding new molecular targets of two copper(II)-hydrazone complexes on triple-negative breast cancer cells using mass-spectrometry-based quantitative proteomics

Balsa, Lucía Mariana; Rodríguez, María Rosa; Ferraresi Curotto, Verónica; Parajón Costa, Beatriz Susana; González Baró, Ana Cecilia; León, Ignacio Esteban (2023)

Vanadium and cancer treatment: In vitro evidences

Leon, Ignacio Esteban; Etcheverry, Susana Beatriz (Nova Science Publishers, 2019)

Cancer is a group of diseases involving abnormal cell growth. in which the cells grow uncontrollably with the potential of invade and spread to other parts of the body. This group of diseases is one of the main death causes ...

Ru-90@bio-MOF-1: A ruthenium(II) metallodrug occluded in porous Zn-based MOF as a strategy to develop anticancer agents

Universidade Estadual Paulista (Unesp); Universidade de São Paulo (USP) (2021-05-01)

One of the major challenges in the field of biomedicine is to use biocompatible carriers to achieve efficient drug delivery in the body. Most of the existing carriers have shown poor loading and rapid drug release. In this ...