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Anti-citrullinated protein antibodies and arthritis in Sjögren’s syndrome: a systematic review and meta-analysis
Objective: The presence of anti-citrullinated protein antibodies (ACPAs) in primary Sjögren’s syndrome (pSS) ranges from 3% to 9.9%; however, there is no agreement about their clinical significance. Our aim was to ...
Abatacept blocks anti-citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO-dependent manner
(BioMed Central, 2018)
Abstract
Background
The anti-inflammatory effect of abatacept is most pronounced in patients with high-titer autoantibodies (including anticitrullinated protein antibodies ...
The presence of anti-citrullinated protein antibodies (ACPA) does not affect the clinical response to adalimumab in a group of RA patients with the tumor necrosis factor (TNF) α-308 G/G promoter polymorphism
(Springer, 2011)
The introduction of antitumor necrosis factor
(TNF) agents has improved the outcome for many patients
with rheumatoid arthritis (RA). To date, the only replicated
genetic predictor of anti-TNF response is the −308 G > ...
Anticorpos antiproteínas citrulinadas e a artrite reumatóide
(Sociedade Brasileira de Reumatologia, 2007-06-01)
Rheumatoid arthritis (RA) patients have a variety of auto-antibodies in the serum and synovial fluid. Among these auto-antibodies, those directed against citrullinated proteins are distinguished because that are specific ...
The presence of anti-citrullinated protein antibodies (ACPA) and rheumatoid factor on patients with rheumatoid arthritis (RA) does not interfere with the chance of clinical remission in a follow-up of 3 years
(SPRINGER HEIDELBERGHEIDELBERG, 2012)
Autoantibodies in early rheumatoid arthritis (RA) have important diagnostic value. The association between the presence of autoantibodies against cyclic citrullinated peptide and the response to treatment is controversial. ...