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Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride
(Elsevier Science, 2015-10)
Two new potential impurities of antiarrhythmic drug substance Dronedarone Hydrochloride together with debutyldronedarone were detected by LC?MS analysis during process development. A successful synthetic strategy for the ...
The emerging role of amiodarone and dronedarone in Chagas disease. Gustavo Benaim and Alberto E. Paniz Mondolfi
(NATURE REVIEWS | CARDIOLOGY (Nat. Rev. Cardiol), 2013)
ACAO ANTIARRITMICA DA METOCLOPRAMIDA (PLASIL®) EM INTOXICACAO DIGITALICA EXPERIMENTAL. COMPARACAO COM A DIFENIL-HIDANTOINA
(1982-12-01)
The antiarrhythmic action of metoclopramide in cardiac arrhythmias caused by toxic doses of desacetyl-lanatoside C and digitoxin was studied in dogs. A comparison was made between the efficacy of metoclopramide and ...
ACAO ANTIARRITMICA DA METOCLOPRAMIDA (PLASIL®) EM INTOXICACAO DIGITALICA EXPERIMENTAL. COMPARACAO COM A DIFENIL-HIDANTOINA
(1982-12-01)
The antiarrhythmic action of metoclopramide in cardiac arrhythmias caused by toxic doses of desacetyl-lanatoside C and digitoxin was studied in dogs. A comparison was made between the efficacy of metoclopramide and ...
Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents
(2006)
The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes. Synthetic phenothiazines (with aliphatic, ...
Medical treatment of cardiac arrhythmias in Chagas'heart disease
(Associação Paulista de Medicina - APM, 1995-04-01)
There are no controlled clinical trials evaluating drug therapy in patients with ventricular arrhythmias and chronic chagasic cardiomyopathy. Empirical treatment with disopyramide (400-1,000mg/d), phenytoin (4-6mg/d), ...