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Toxicity, Teratogenicity and Anti-cancer Activity of α-solanine: A Perspective on Anti-cancer Potential
The α-Solanine is a glycoalkaloid metabolite produced by solanaceae species, important plant food in the human nutrition. This α-solanine is highly toxic to animals and humans and has been indicated as a risk factor for ...
Produtos Naturais em Fase Avançada de Testes Clínicos no Tratamento contra o Câncer
(Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde., 2017)
Anti-cancer effect of lactic acid bacteria expressing antioxidant enzymes or IL-10 in a colorectal cancer mouse model
(Elsevier Science, 2017-01)
The association between inflammatory bowel diseases and colorectal cancer is well documented. The genetic modification of lactic acid bacteria as a tool to increase the anti-inflammatory potential of these microorganisms ...
Encapsulating Anti-Parasite Benzimidazole Drugs into Lipid-Coated Calcium Phosphate Nanoparticles to Efficiently Induce Skin Cancer Cell Apoptosis
(2021-06-15)
Benzimidazole (BMZ) family of anti-worm drugs has been now repurposed as anti-cancer drugs. However, offering a general reformulation method for these drugs is essential due to their hydrophobicity and low aqueous solubility. ...
Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide
(2017-06-01)
Polybia-MP1 (IDWKKLLDAAKQIL-NH2) is a lytic peptide from the Brazilian wasp venom with known anti-cancer properties. Previous evidence indicates that phosphatidylserine (PS) lipids are relevant for the lytic activity of ...
A conjugate of the lytic peptide Hecate and gallic acid: structure, activity against cervical cancer, and toxicity
(Springer, 2015-07-01)
Conjugate compounds constitute a new class of molecules of important biological interest mainly for the treatment of diseases such as cancer. The N-terminus region of cationic peptides has been described as important for ...
Uso de productos naturales como terapia alternativa anti-cancerosa: riesgos de interacciones con fármacos anti-cancerosos convencionales
(2008)
Muchas culturas han usado las plantas para tratar afecciones médicas y un porcentaje de las medicinas modernas son obtenidas a partir de las plantas. Hoy en día varias hierbas han sido usadas para el tratamiento del cáncer ...
Antitumoral, mutagenic and (anti)estrogenic activities of tingenone and pristimerin
(Soc Brasileira Farmacognosia, 2011-11-01)
Cancer constitutes the second main mortality cause in the world, after cardiovascular diseases. In spite of the progresses in the chemotherapeutics treatments, many patients fail chemotherapy, mainly because of side effects ...
Antitumoral, mutagenic and (anti)estrogenic activities of tingenone and pristimerin
(Soc Brasileira Farmacognosia, 2011-11-01)
Cancer constitutes the second main mortality cause in the world, after cardiovascular diseases. In spite of the progresses in the chemotherapeutics treatments, many patients fail chemotherapy, mainly because of side effects ...