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Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson’s disease
(Taylor and Francis Ltd, 2017)
Isoflavone genistein inhibits the angiotensin-converting enzyme and alters the vascular responses to angiotensin I and bradykinin
(ELSEVIER SCIENCE BV, 2009)
Genistein produces antihypertensive and beneficial cardiovascular effects, although the mechanisms for these effects are not known. We examined whether genistein inhibits the in vivo responses to angiotensin I or enhances ...
Evidence for changes in the tachyphylactic property of recombinant angiotensin II AT(1) receptor expressed in CHO cells
(Elsevier B.V., 2002-03-29)
The manifestation of tachyphylaxis to angiotensin 11 in Chinese hamster ovary (CHO) cells expressing the rat angiotensin II AT(1) receptor was investigated. the cells were transfected with a cDNA fragment containing the ...
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension
(Elsevier Inc., 2018)
© 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
Hypercholesterolemia modifies angiotensin II desensitisation and cross talk between α1-adrenoceptor and angiotensin AT1 receptor in rabbit aorta
(Elsevier Science, 2010-06)
This study characterised the effect of a hypercholesterolemic diet on the interactions of hormone receptors in the rabbit aorta, both in homologous desensitisation to angiotensin II and cross talk between α1-adrenoceptors ...
Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9)
(Elsevier, 2015)
Insulin-like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9) have been proposed to be important mediators in cardioprotection. A large body of evidence indicates that insulin like growth factor-1 has pleotropic ...
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/ang ii axis
(UNIV CATOLICA DE VALPARAISO, 2014)
Background: Little is known about the biological effects of angiotensin-(1-9), but available evidence shows that angiotensin-(1-9) has beneficial effects in preventing/ameliorating cardiovascular remodeling. Objective: In ...