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Relationship between androgen receptor gene structure and protein function. Structural gene defects that promote androgen insensitivity in man Estructura del gen del receptor de andrógeno y función de la proteína. Defectos estructurales del gen que determ
(1996)
The human androgen receptor is a member of the superfamily of steroid hormone receptors and contains three functional domains: an amino-terminal region involved in the expression of androgen regulated genes, a central ...
Androgen receptor signaling in prostate cancer: Genetic and molecular aspects
(2014-01-01)
The prostate is an accessory sex gland of the male reproductive system, which produces alkaline prostatic fluid, capable of ensuring the spermatic viability to fertilize eggs within the female reproductive system. Functionally, ...
Modulation of androgen receptor protein by culture conditions of human skin fibroblasts
(2002)
Cultures of skin fibroblasts show variation of androgen binding with culture conditions; binding variations are usually avoided by using confluent cultures. In this work, we analysed the effect of cell density and mitogenic ...
Excess androgen during perinatal life alters steroid receptor expression, apoptosis, and cell proliferation in the uteri of the offspring
(2013-09-01)
Exposure to environmental chemicals may contribute to reproductive disorders, especially when it occurs in critical periods of development. The female reproductive system can be a target for androgens derived from environmental ...
Excess androgen during perinatal life alters steroid receptor expression, apoptosis, and cell proliferation in the uteri of the offspring
(2013-09-01)
Exposure to environmental chemicals may contribute to reproductive disorders, especially when it occurs in critical periods of development. The female reproductive system can be a target for androgens derived from environmental ...
Subcellular Localization and Physiological Roles of Androgen Receptor
(Bentham Science Publishers, 2019)
Androgens, such as testosterone and Dihydrotestosterone (DHT), exert theiractions through the Androgen Receptor (AR), a ligand-dependent nuclear transcription factor that belongs to the steroid hormone nuclear receptor ...
Androgen receptors and experimental bone loss - an in vivo and in vitro study
(Elsevier B. V., 2015)
Testosterone is a sex hormone that exhibits many functions beyond reproduction; one such function is the regulation of bone metabolism. The role played by androgen receptors during testosterone-mediated biological processes ...
"In vitro" response of fibroblasts from genital skin to androgens Respuesta in vitro de fibroblastos de piel genital humana a andrógenos
(1996)
Defects of androgen receptor gen (Xc 11-12) leadre cellular insensitivity to these steroids. Androgen action is curently measured 'in vitro' in cultures of fioroblosts from genral skin, since expression of the androgen ...
Androgen receptors and experimental bone loss - an in vivo and in vitro study
(Elsevier B. V., 2015)