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Structural insights into selectivity and cofactor binding in snake venom l-amino acid oxidases
(2012-04-27)
l-Amino acid oxidases (LAAOs) are flavoenzymes that catalytically deaminate l-amino acids to corresponding α-keto acids with the concomitant production of ammonia (NH 3) and hydrogen peroxide (H 2O 2). Particularly, snake ...
Structural insights into selectivity and cofactor binding in snake venom l-amino acid oxidases
(2012-04-27)
l-Amino acid oxidases (LAAOs) are flavoenzymes that catalytically deaminate l-amino acids to corresponding α-keto acids with the concomitant production of ammonia (NH 3) and hydrogen peroxide (H 2O 2). Particularly, snake ...
Platelet aggregation and antibacterial effects of an L-amino acid oxidase purified from Bothrops alternatus snake venom
(Elsevier B.V., 2004-06-01)
The isolation and biochemical/enzymatic characterization of an L-amino acid oxidase, Balt-LAAO-I, from Bothrops alternates snake venom, is described. Balt-LAAO-I is an acidic glycoprotein, pI similar to 5.37, homodimeric, ...
Platelet aggregation and antibacterial effects of an L-amino acid oxidase purified from Bothrops alternatus snake venom
(Elsevier B.V., 2004-06-01)
The isolation and biochemical/enzymatic characterization of an L-amino acid oxidase, Balt-LAAO-I, from Bothrops alternates snake venom, is described. Balt-LAAO-I is an acidic glycoprotein, pI similar to 5.37, homodimeric, ...
Crystallization and preliminary X-ray diffraction analysis of an l-amino-acid oxidase from Bothrops jararacussu venom
(Wiley-Blackwell, 2012-02-01)
Snake-venom l-amino-acid oxidases (SV-LAAOs) trigger a wide range of local and systematic effects, including inhibition of platelet aggregation, cytotoxicity, haemolysis, apoptosis and haemorrhage. These effects mainly ...
A rational protocol for the successful crystallization of l-amino-acid oxidase from Bothrops atrox
(WILEY-BLACKWELL, 2011)
Despite the valuable contributions of robotics and high-throughput approaches to protein crystallization, the role of an experienced crystallographer in the evaluation and rationalization of a crystallization process is ...
Snake venom L-amino acid oxidases: an overview on their antitumor effects
(BMC, 2014-06-02)
The L-amino acid oxidases (LAAOs) constitute a major component of snake venoms and have been widely studied due to their widespread presence and various effects, such as apoptosis induction, cytotoxicity, induction and/or ...
Antimicrobial activity of an l-amino acid oxidase isolated from bothrops leucurus snake venom
(2010-01-01)
Some snake venom proteins present enzymatic activities, such as L-amino acid oxidase (LAAO). The aim of this paper was to investigate the effect of Bothrops leucurus total venom (BleuTV) and its fraction LAAO (BleuLAAO) ...