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Alternative pathways for angiotensin II generation in the cardiovascular system
(Associação Brasileira de Divulgação Científica, 2011)
The classical renin-angiotensin system (RAS) consists of enzymes and peptides that regulate blood pressure and electrolyte and fluid homeostasis. Angiotensin II (Ang II) is one of the most important and extensively studied ...
Alternative Pathways in Science and Industry: Activism, Innovation, and the Environment in an Era of Globalization
(Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Cientifica e Tecnológica em Saúde., 2007)
Modulators of complement activation: a patent review (2008 - 2013)
(Informa Healthcare, 2014-03)
Introduction: The architecture of the complement system has evolved during the last 600 – 700 million years to become an amazingly efficient and highly versatile alerting and cell killing device. Under physiological ...
Activation of the alternative pathway of complement during the acute phase of typical haemolytic uraemic syndrome
(Wiley, 2015-06)
Haemolytic uraemic syndrome (HUS) is characterized by haemolytic anaemia, thrombocytopenia and acute renal failure. We studied the activation state of classical and alternative pathways of complement during the acute phase ...
Interferon-γ, interleukins-6 and -4, and factor XIII-A as indirect markers of the classical and alternative macrophage activation pathways in chronic periodontitis
(American Academy of Periodontology, 2014)
Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ ...
Critical Appraisal Of Eculizumab For Atypical Hemolytic Uremic Syndrome
(Dove Medical Press LtdAlbany, 2016)