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Activin-inhibitory action on lactotrophs is decreased in lactotroph hyperplasia
(BioScientifica, 2020-02)
Among all the hormone-secreting pituitary tumours, prolactinomas are the most frequently found in the clinic. Since dopamine is the primary inhibitor of lactotroph function, dopamine agonists represent the first-line ...
Activin-inhibitory action on lactotrophs is decreased lactotroph hyperplasia
(BioScientifica, 2019-12)
Among all the hormone-secreting pituitary tumours, prolactinomas are the mostfrequently found in the clinic. Since dopamine is the primary inhibitor of lactotroph function, dopamine agonists represent the first-line therapy. ...
Inhibition of mesoderm formation by follistatin
(1998)
Mesoderm induction requires interaction between cells of the animal and vegetal hemispheres of the embryo. Several molecules have been proposed as candidates for mesoderm-inducing signals, with activin a particularly strong ...
Diagnostic value of serum activin A and follistatin levels in women with peritoneal, ovarian and deep infiltrating endometriosis
(OXFORD UNIV PRESSOXFORD, 2012)
Activin A is a growth factor, produced by the endometrium, whose actions are modulated by the binding protein follistatin. Both proteins are detectable in the peripheral serum and their concentrations may be increased in ...
Expressão local e sistêmica da ativina A e folistatina e seus efeitos biológicos in vitro na endometriose
(Universidade Federal de Minas GeraisUFMG, 2011-10-06)
Objective: To evaluate the expression pattern of activin A, activin receptors, and activin modulators messenger RNA (mRNA) in the eutopic endometrium of patients with endometriosis at different phases of the menstrual cycle ...
Gilz-Activin A as a Novel Signaling Axis Orchestrating Mesenchymal Stem Cell and Th17 Cell Interplay
(2018)
Mesenchymal stem cells (MSC) are highly immunosuppressive cells able to reduce chronic inflammation through the active release of mediators. Recently, we showed that glucocorticoid-induced leucine zipper (Gilz) expression ...
Regulation of inhibin/activin expression in rat early antral follicles
(Elsevier Ireland, 2009-10)
The aim of the present study was to determine the endocrine activity of cultured early antral follicles (EAF) isolated from prepubertal diethylstilbestrol-treated rats. The effect of steroidogenic substrates and FSH on ...