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Postprandial proximal gastric acid pocket and gastroesophageal reflux disease
(Wiley-Blackwell, 2012-09-01)
An unbuffered layer of acidity that escapes neutralization by food has been demonstrated in volunteers and gastroesophageal reflux disease patients. This postprandial proximal gastric acid pocket (PPGAP) is manometrically ...
Influence of dental exposure to oral environment on smear layer removal and collagen exhibition after using different conditioning agents
(2011-12-28)
Although in vitro studies have shown encouraging results for root surface conditioning with demineralizing agents, in vivo studies have failed to show its benefits in periodontal healing. This can be attributed to several ...
Influence of dental exposure to oral environment on smear layer removal and collagen exhibition after using different conditioning agents
(2011-12-28)
Although in vitro studies have shown encouraging results for root surface conditioning with demineralizing agents, in vivo studies have failed to show its benefits in periodontal healing. This can be attributed to several ...
Effects of vitamin-B complex supplementation on periodontal wound healing
(Amer Acad PeriodontologyChicagoEUA, 2005)
The Octahydroindene Carboxyl Substructure from Dihydrobetulinic Acid is Essential to Inhibit Topoisomerase IB from Leishmania donovani
(Soc Brasileira Quimica, 2016-03-01)
The dihydrobetulinic acid is a known competitive inhibitor of topoisomerase IB from Leishmania donovani, a validated target for developing new antileishmanial drugs. However, its binding mode and interaction pocket have ...
Mapping the catalytic pocket of phospholipases A2 and C using a novel set of phosphatidylcholines
(Portland Press, 2000-03)
A set of radioiodinatable phosphatidylcholines (PCs) derivatized with the Bolton-Hunter reagent (BHPCs) was synthesized to probe the substrate recognition and activity of phospholipases. A common feature of this series is ...
Cationic amino acid uptake constitutes a metabolic regulation mechanism and occurs in the flagellar pocket of trypanosoma cruzi
(Public Library of Science, 2012-02)
Trypanosomatids' amino acid permeases are key proteins in parasite metabolism since they participate in the adaptation of parasites to different environments. Here, we report that TcAAP3, a member of a Trypanosoma cruzi ...
Functional role of water in membranes updated: A tribute to Träuble
(Elsevier Science, 2015-07)
The classical view of a cell membrane is as a hydrophobic slab in which only nonpolar solutes can dissolve and permeate. However, water-soluble non-electrolytes such as glycerol, erythritol, urea and others can permeate ...
Heme pocket structural properties of a bacterial truncated hemoglobin from thermobifida fusca
(American Chemical Society, 2010-12)
An acidic surface variant (ASV) of the "truncated" hemoglobin from Thermobifida fusca was designed with the aim of creating a versatile globin scaffold endowed with thermostability and a high level of recombinant expression ...