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Effect of Risperidone and Fluoxetine on the Movement and Neurochemical Changes of Zebrafish
(Scientific Research Publishing, 2012-11)
Brain developmental disorders in humans, including Autism Spectrum Disorders (ASD) and Down’s syndrome, have been linked to increased serotonin levels. This work was designed to study changes in serotonin levels in the ...
Relation between biophysical properties of nanostructures and their toxicity on zebrafish
(Springer Verlag Berlín, 2017-10)
In recent years, the use of commercial nanoparticles in different industry and health fields has increased exponentially. However, the uncontrolled application of nanoparticles might present a potential risk to the environment ...
Optimization and in vivo toxicity evaluation of G4.5 PAMAM dendrimer-risperidone complexes
(Public Library of Science, 2014-02)
Risperidone is an approved antipsychotic drug belonging to the chemical class of benzisoxazole. This drug has low solubility in aqueous medium and poor bioavailability due to extensive first-pass metabolism and high protein ...
Folic acid magnetic nanotheranostics for delivering doxorubicin: Toxicological and biocompatibility studies on Zebrafish embryo and larvae
(Academic Press Inc Elsevier Science, 2018-11)
Doxorubicin (DOXO) is a chemotherapeutic agent widely used for the treatment of solid tumors and hematologic malignancies in both adults and children. However, DOXO causes short- and long-term cardiotoxicity and others ...
Light/dark cycles modulate asymmetric parapineal connectivity to the left habenula in zebrafish larvae
(2017)
Introduction: Parapineal (PpO) neurons develop asymmetric connectivity to the left habenula (lHb) in the dorsal diencephalon of embryonic and larval zebrafish. Recent studies relate this asymmetric connectivity with sensory ...
Biological response and developmental toxicity of zebrafish embryo and larvae exposed to multi-walled carbon nanotubes with different dimension
(Elsevier, 2019-08)
The development and use of nanomaterials are increasing significantly. Among nanomaterials, carbon nanotubes are of particular interest due to its distinctive physicochemical properties. This material composed of sheets ...
Nutraceutical emulsion containing valproic acid (NE-VPA): a drug delivery system for reversion of seizures in zebrafish larvae epilepsy model
(Springer Netherlands, 2017-09)
Valproic acid (VPA) is an antiepileptic drug, which is currently used in neurodegenerative diseases. However, a high dose is required to obtain a therapeutic effect. Long-chain polyunsaturated fatty acids (PUFAs), such as ...
E-cadherin expression pattern during zebrafish embryonic epidermis development [version 3; referees: 3 approved]
(F1000 Research Ltd, 2018-12)
Background: E-cadherin is the major adhesion receptor in epithelial adherens junctions (AJs). On established epidermis, E-cadherin performs fine-tuned cell-cell contact remodeling to maintain tissue integrity, which is ...