Buscar
Mostrando ítems 1-10 de 35
Early improvement of psychotic symptoms with lithium monotherapy as a predictor of later response in mania
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Although lithium has been the first line agent in the treatment of bipolar disorder (BD), few studies have evaluated lithium's efficacy in mania with psychosis and its association with later response. Furthermore, given ...
Plasma cortisol in first episode drug-naive mania: Differential levels in euphoric versus irritable mood
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Background: Dysregulation of HPA axis has been widely described in subjects with bipolar disorder (BD), including changes in cortisol levels during mood episodes and euthymia. However, most of the studies were done with ...
Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: A preliminary 4-week study
(ELSEVIER IRELAND LTD, 2011)
Several studies have suggested an important role for brain-derived neurotrophic factor (BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms underlying the therapeutic effects of lithium ...
Lurasidone Efficacy in Mixed Depressive States A Comparison of Standard Rating Scales to the Koukopoulos Mixed Depression Rating Scale
(Lippincott Williams & Wilkins, 2020)
Introduction A new mood rating scale for mixed states of depression along with manic-like excitatory
symptoms, the Koukopoulos Mixed Depression Rating Scale (KMDRS), was assessed in a post hoc
analysis of a randomized ...
Desfechos propostos em protocolos de estudos clínicos que avaliam opções de tratamento farmacológico da mania
(Universidade Federal de São Paulo, 2022-12-19)
Introdução: Um processo importante do planejamento dos protocolos de estudos
clínicos é a seleção dos desfechos, pois é por meio deles que se avaliam o quanto
os tratamentos podem ou não contribuir para a melhora ou cura ...
Avaliação de fatores neurotróficos e marcadores imunológicos em indivíduos com transtorno bipolar
(Universidade Federal de Minas GeraisUFMG, 2012-05-25)
Introduction: Bipolar disorder (BD) is a prevalent and chronic illness associated with substantial morbidity. There is a growing body of evidence indicating that disturbance at neurotrophic factors and immunologic parameters ...
The Koukopoulos Mixed Depression Rating Scale (KMDRS): an International Mood Network (IMN) validation study of a new mixed mood rating scale
(Elsevier, 2018)
Background: It has been proposed that the broad major depressive disorder (MDD) construct is heterogenous.
Koukopoulos has provided diagnostic criteria for an important subtype within that construct, "mixed depression"
(MxD), ...
Estudo da concentração plasmática de TNF-alfa e seus receptores solúveis em pacientes com transtorno bipolar
(Universidade Federal de Minas GeraisUFMG, 2010-08-09)
Introduction: Bipolar disorder (BD) has been associated with a proinflammatory state in which TNF-alfa seems to play a relevant role.Objective: The aim of the present study was to evaluate the plasma levels of TNF-alfa and ...