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Extracellular matrix stiffness and Wnt/β-catenin signaling in physiology and disease
(NLM (Medline), 2020)
Wnt signaling modulates pre- and postsynaptic maturation: therapeutic considerations
(2010)
Wnt signaling regulates a wealth of aspects of nervous system development and function in embryonic stages and in adulthood. The expression of Wnt ligands and components of the Wnt signaling machinery in early stages of ...
Wnt5a promotes differentiation and development of adult-born neurons in the hippocampus by noncanonical Wnt signaling
(Facultad de Medicina y Ciencia, 2020)
In the adult hippocampus, new neurons are generated in the dentate gyrus. The Wnt signaling pathway regulates this process, but little is known about the endogenous Wnt ligands involved. We investigated the role of Wnt5a ...
Expresión proteica y regulación por estradiol y progesterona de Wnt-7a y Wnt-5a en tres regiones de útero con miomatosis
(2011-11-28)
Introduction: The uterine fibroid tumor is most common female genital tract disease and is the most common cause of gynecologic pelvic surgery. It's a classic gynecologic pathology in which almost everything is apparently ...
Wnt5a promotes differentiation and development of adult-born neurons in the hippocampus by noncanonical Wnt signaling
(2020)
In the adult hippocampus, new neurons are generated in the dentate gyrus. The Wnt signaling pathway regulates this process, but little is known about the endogenous Wnt ligands involved. We investigated the role of Wnt5a ...
Wnt-regulated dynamics of positional information in zebrafish somitogenesis
(Company Of Biologists, 2014-03)
How signaling gradients supply positional information in a field of moving cells is an unsolved question in patterning and morphogenesis. Here, we ask how a Wnt signaling gradient regulates the dynamics of a wavefront of ...
Wnt-induced activation of glucose metabolism mediates the in vivo neuroprotective roles of Wnt signaling in Alzheimer disease
(WILEY, 2019)
Dysregulated Wnt signaling is linked to major neurodegenerative diseases, including Alzheimer disease (AD). In mouse models of AD, activation of the canonical Wnt signaling pathway improves learning/memory, but the mechanism ...
Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage
(2013-03-01)
Objectives were to evaluate the role of canonical WNT signaling in development of the preimplantation embryo. Signaling was activated with 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine (AMBMP) ...
Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage
(2013-03-01)
Objectives were to evaluate the role of canonical WNT signaling in development of the preimplantation embryo. Signaling was activated with 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine (AMBMP) ...