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Autophagy, Warburg, and Warburg reverse effects in human cancer
(Hindawi Publishing Corporation, 2014-08)
Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized ...
A genetically encoded fret lactate sensor and its use to detect the warburg effect in single cancer cells
(PUBLIC LIBRAY OF SCIENCE, 2013)
Melatonin reverses the Warburg-dependent effect in ovarian cancer cell by binding to the MT1 and MT2 receptors
(Elsevier B.V., 2020-09-01)
Defining the Molecular Basis of Tumor Metabolism: a Continuing Challenge Since Warburg's Discovery
(Karger, 2011-01-01)
Cancer cells are the product of genetic disorders that alter crucial intracellular signaling pathways associated with the regulation of cell survival, proliferation, differentiation and death mechanisms. the role of oncogene ...
Metabolism and brain cancer
(Faculdade de Medicina / USP, 2011)
Cellular energy metabolism is one of the main processes affected during the transition from normal to cancer cells, and it is a crucial determinant of cell proliferation or cell death. As a support for rapid proliferation, ...
Metabo-Devo: A metabolic perspective of development
(Elsevier Science, 2018-12)
In the last years, several reports have established the notion that metabolism is not just a housekeeping process, but instead an active effector of physiological changes. The idea that the metabolic status may rule a wide ...
Effects of larval rearing substrates on some life-table parameters of Lutzomyia longipalpis sand flies
(Public Library of Science, 2021)
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation
(Nature Publishing Group, 2019-12)
Regulation of the energetic metabolism occurs fundamentally at the cellular level, so analytical strategies must aim to attain single cell resolution to fully embrace its inherent complexity. We have developed methods to ...
Acid-mediated tumor invasion as a function of nutrient source location
(American Physical Society, 2019-08-29)
Cancer cells have an altered metabolism that increases acid production driving to an extracellular pH significantly lower than normal. This leads to normal cell death, and extracellular matrix degradation allowing the ...