In recent years, nanoparticulate systems have matured from simple devices to multifunctional and more complex systems. They are biodegradable, stable in blood, non-toxic, and non immunogenic construct, capable of delivering ...

Bevacizumab is an FDA approved monoclonal antibody (anti VEGF) indicated in many cancers, mostly metastatic ones. D-α-tocopheryl polyethylene glycol succinate (TPGS) is the water-soluble form of vitamin E which usually ...

A colestase crônica por ligadura e ressecção do ducto biliar em ratos jovens é freqüentemente utilizada como modelo experimental de atresia biliar. Na colestase ocorre má absorção de vitamina E com resultante estresse ...

© 2016 Elsevier B.V.The effect of different plasticizers (glycerol, vitamin E TPGS and triacetin) and their concentrations on the physico-mechanical properties of pullulan based oral films was studied. A full factorial ...

© 2017 Elsevier B.V. The aim of the present work was to prepare tadalafil (TDF) nanocrystals-loaded oral polymeric films (OFs) and investigate the effect of hydrophilic surfactants and drug loads on the physico-mechanical ...

The aim of the present work was to prepare tadalafil (TDF) nanocrystals-loaded oral polymeric films (OFs) and investigate the effect of hydrophilic surfactants and drug loads on the physico-mechanical and dissolution ...

Nanotechnology has been applied in the medicine field to improve the treatment of a wide range of diseases. However, to reach the nanomedicines delivery to desirable target tissue for promote an enhancement of pharmacological ...