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Development of a Reverse Genetic System to Generate Recombinant Chimeric Tacaribe Virus that Expresses Junín Virus Glycoproteins
(Molecular Diversity Preservation International, 2020-11)
Mammarenaviruses are enveloped and segmented negative-stranded RNA viruses that comprise several pathogenic members associated with severe human hemorrhagic fevers. Tacaribe virus (TCRV) is the prototype for the New World ...
Human transferrin receptor triggers an alternative Tacaribe virus internalization pathway
(Springer Wien, 2016-02)
Tacaribe virus (TCRV) entry occurs by receptor-mediated endocytosis. To explore the entry mechanism used by TCRV, the inhibitory effects of drugs and dominant negative (DN) constructions affecting the main endocytic pathways ...
Role of the ERK1/2 signaling pathway in the replication of junín and tacaribe viruses
(MDPI, 2018-04)
We have previously shown that the infection of cell cultures with the arenaviruses Junín (JUNV), Tacaribe (TCRV), and Pichindé promotes the phosphorylation of mitogen-activated protein kinases (MAPKs) extracellular ...
Mapping of the Tacaribe Arenavirus Z-Protein Binding Sites on the L Protein Identified both Amino Acids within the Putative Polymerase Domain and a Region at the N Terminus of L That Are Critically Involved in Binding
(American Society for Microbiology, 2008-09)
Tacaribe virus (TacV) is the prototype of the New World group of arenaviruses. The TacV genome encodes four proteins: the nucleoprotein (N), the glycoprotein precursor, the polymerase (L), and a RING finger protein (Z). ...
Mode of inactivation of arenaviruses by disulfide-based compounds
(Elsevier Science, 2002-12)
Several disulfide-based compounds, including intermolecular aromatic disulfides of the type Ph-S-S-Ph and dithianes with the sulfur atoms tethered in a ring structure, have shown effective inhibitory activity against the ...
Arenavirus : Persistencia de los virus Junín (FHA) y Tacaribe en células cultivadas in vitro
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 1978)
Interacciones de los Arenavirus Tacaribe y Junín con sus células hospedadoras en las etapas tempranas de la infecciónInteractions of Tacaribe and Junin arenavirus with their host cells during early stage of infection
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2015)
Uncovering viral protein-protein interactions and their role in arenavirus life cycle
(MDPI, 2012-09)
The Arenaviridae family includes widely distributed pathogens that cause severe hemorrhagic fever in humans. Replication and packaging of their single-stranded RNA genome involve RNA recognition by viral proteins and a ...
Adaptación de una ELISA IgG para detección de anticuerpos contra Arenavirus del Complejo Tacaribe en pacientes del Hospital Local de Montelíbano, Córdoba
(Universidad de los AndesMicrobiologíaFacultad de CienciasDepartamento de Ciencias Biológicas, 2020)
"La infección en humanos por Arenavirus pertenecientes al Complejo Tacaribe puede conllevar al desarrollo de fiebres hemorrágicas y alteraciones en el sistema nervioso central. En Colombia se ha reportado la presencia del ...