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Diffuse Intrinsic Brainstem Tumor in an Infant: A Case of Therapeutic Efficacy With Vinorelbine
(Lippincott Williams & Wilkins, 2011-03-01)
Brainstem gliomas constitute 10% to 20% of all pediatric tumors of the central nervous system, and diffusely infiltrative brainstem gliomas are the most common brainstem tumors associated with a poor prognosis. A small ...
Single agent vinorelbine in pediatric patients with progressive optic pathway glioma
(Springer, 2015-01-01)
The management of progressive unresectable low-grade glioma remains controversial. Treatment options have included radiotherapy, and more recently chemotherapy, usually following an initial period of observation. Within ...
In vitro inhibition of murine hematopoietic progenitors and stromal cells by vinorelbine
(Springer, 2000-04)
Hematopoietic progenitor colony assays were used to establish the effects of the vinca alkaloid vinorelbine (VRB) on murine bone marrow. The in vitro growth of colony-forming units-granulocyte/macrophage (CFU-GM), burst ...
Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
(2010)
This review demonstrates the importance of plants as sources of molecules used in anticancer therapies. The approach is performed by relating the active molecules to their origins, details, mechanisms of action, ...
Recent treatment advances in HER2-positive metastatic breast cancer: a clinical approach
(2012-05)
The use of targeted therapy directed against HER2 is currently the standard of care in patients with metastatic HER2-positive breast cancer. The combination of trastuzumab with a taxane as first-line treatment in HER2-positive ...