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Vibrational Circular Dichroism Absolute Configuration of 9,12-Cyclomulin-13-ol, a Diterpene from Azorella and Laretia Species
(Nature, 2015)
The absolute configuration of the diterpenoid 9,12-cyclomulin-13-ol (1), a constituent of Azorella
and Laretia species, has been established by vibrational circular dichroism spectroscopy in
combination with density ...
Absolute configuration of sargaol acetate using DFT calculations and vibrational circular dichroism
(2010)
The absolute configuration (AC) of sargaol acetate (2), isolated from the brown alga Stypopodium flabelliforme, was determined using vibrational circular dichroism (VCD) measurements and density functional theory (DFT) ...
Albendazole sulfoxide enantiomers: Preparative chiral separation and absolute stereochemistry
(Elsevier Science BvAmsterdamHolanda, 2012)
Pushing the boundaries of VCD spectroscopy in natural product chemistry
(RSC, 2023-05-11)
Vibrational circular dichroism (VCD) is one of the most powerful techniques to assess the stereochemistry of chiral molecules in solution state. The need for quantum chemical calculations to interpret experimental data, ...
Vibrational circular dichroism of africanane and lippifoliane sesquiterpenes from Lippia integrifolia
(American Chemical Society, 2008)
Tackling Stereochemistry in Drug Molecules with Vibrational Optical Activity
(MDPI, 2021)
Chirality plays a crucial role in drug discovery and development. As a result, a significant number of commercially available drugs are structurally dissymmetric and enantiomerically pure. The determination of the exact ...
Albendazole sulfoxide enantiomers: Preparative chiral separation and absolute stereochemistry
(Elsevier B.V., 2012-03-23)
The enantiomeric separation of albendazole sulfoxide was carried out by simulated moving bed chromatography with variable zones (VARICOL). An overall recovery of 97% was achieved and enantiomeric ratios of 99.5% for raffinate ...
Albendazole sulfoxide enantiomers: Preparative chiral separation and absolute stereochemistry
(Elsevier B.V., 2012-03-23)
The enantiomeric separation of albendazole sulfoxide was carried out by simulated moving bed chromatography with variable zones (VARICOL). An overall recovery of 97% was achieved and enantiomeric ratios of 99.5% for raffinate ...
Vibrational circular dichroism for the assignment of absolute configuration of natural products in Brazil
(Springer, 2021-12-02)
The determination of the absolute configuration of chiral bioactive natural products is a crucial step in their structural characterization.
Several well-established techniques, such as X-ray crystallography, stereo-controlled ...