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Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis
(Public Library of Science, 2015)
Cysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. ...
Cytokine-enhanced vaccine and suicide gene therapy as adjuvant treatments of metastatic melanoma in a horse
(British Veterinary Association, 2009-02)
We evaluated the safety, efficacy and anti-tumour effects of a surgery adjuvant treatment on an equine patient with metastatic malignant melanoma. This approach combined suicide gene therapy with a subcutaneous vaccine ...
Therapeutic potential of bleomycin plus suicide or interferon-β gene transfer combination for spontaneous feline and canine melanoma
(Impact Journals, 2017-12)
We originated and characterized melanoma cell lines derived from tumors of two feline and two canine veterinary patients. These lines reestablished the morphology, physiology and cell heterogeneity of their respective ...
Gene therapy for canine cancer: clinical results
(Nova Science Publishers, 2012)
Despite the important progress obtained in the treatment of some pets malignancies, new treatments need to be developed. In this review we discuss the bases and we summarize the outcomes of published gene therapy veterinary ...
Electroporation as the immunotherapy strategy for cancer in veterinary medicine: state of the art in Latin America
(Multidisciplinary Digital Publishing Institute, 2020-09)
Electroporation is a technology that increases cell membrane permeability by the application of electric pulses. Electrochemotherapy (ECT), the best-known application of electroporation, is a very effective local treatment ...
Combination of suicide and cytokine gene therapies as surgery adjuvant for canine mammary carcinoma
(MDPI, 2018-09)
The incidence of canine mammary carcinoma varies with age, breed, and spay status, being among the main tumors appearing in intact female dogs. Thirty-six canine mammary carcinoma patients received injections of canine ...
Recent clinical trials of cancer immunogene therapy in companion animals
(Baishideng Publishing Group, 2017-05)
This mini-review presents the results of veterinary clinical trials on immunogene therapy published from 2014 to 2016. A variety of tumors, among them melanoma(canine and equine), mastocytoma (canine), mammary adenocarcinoma ...
Cytokine-Enhanced Vaccine and Suicide Non-Viral Gene Therapy in Advanced Metastatic Melanoma Patients: Two Case Reports
(Science Repository, 2020-05)
The prognostic for metastatic melanoma is very poor when treated with standard cytotoxic chemotherapies and it is often refractory to check point inhibitors and/or molecular targets. In this context the development of new ...
Identification and antimicrobial susceptibility of obligate anaerobic bacteria from clinical samples of animal origin
(Anaerobe, 2015-09-14)
The etiology of veterinary infectious diseases has been the focus of considerable research, yet relatively little is known about the causative agents of anaerobic infections. Susceptibility studies have documented the ...
Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals
(Hindawi Publishing Corporation, 2014-11)
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may ...