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VGLUTs and glutamate synthesis-focus on DRG neurons and pain
(MDPI, 2015-12)
The amino acid glutamate is the principal excitatory transmitter in the nervous system, including in sensory neurons that convey pain sensation from the periphery to the brain. It is now well established that a family of ...
VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review
(Hindawi Publishing Corporation, 2013-11)
Vesicular glutamate transporters (VGLUTs) are key molecules for the incorporation of glutamate in synaptic vesicles across the nervous system, and since their discovery in the early 1990s, research on these transporters ...
Glutamate neurotransmission is affected in prenatally stressed offspring
(Pergamon-elsevier Science Ltd, 2015-05)
Previous studies from our laboratory have shown that male adult offspring of stressed mothers exhibited higher levels of ionotropic and metabotropic glutamate receptors than control rats. These offspring also showed ...
Expression of vesicular glutamate transporters in sensory and autonomic neurons innervating the mouse urinary bladder
(Elsevier, 2013-07)
Purpose: Vesicular glutamate transporters (VGLUTs), essential for loading glutamate into synaptic vesicles, are present in various neuronal systems. However, the expression of VGLUTs in neurons innervating the urinary ...
Limiting glutamate transmission in a Vglut2-expressing subpopulation of the subthalamic nucleus is sufficient to cause hyperlocomotion
(2014-04-18)
The subthalamic nucleus (STN) is a key area of the basal ganglia
circuitry regulating movement. We identified a subpopulation of
neurons within this structure that coexpresses Vglut2 and Pitx2,
and by conditional ...
Transcript expression of vesicular glutamate transporters in lumbar dorsal root ganglia and the spinal cord of mice – Effects of peripheral axotomy or hindpaw inflammation
(Elsevier, 2013-05)
Using specific riboprobes, we characterized the expression of vesicular glutamate transporter (VGLUT)1–VGLUT3 transcripts in lumbar 4–5 (L4–5) dorsal root ganglions (DRGs) and the thoracolumbar to lumbosacral spinal cord ...
Transcript expression of vesicular glutamate transporters in rat dorsal root Ganglion and spinal cord neurons: Impact of spinal blockade during hindpaw inflammation
(American Chemical Society, 2020-08)
Studies in mouse, and to a lesser extent in rat, have revealed the neuroanatomical distribution of vesicular glutamate transporters (VGLUTs) and begun exposing the critical role of VGLUT2 and VGLUT3 in pain transmission. ...
Estudio de la concentración de glutamato extracelular en la región ca3 hipocampal de rata hipotiroidea adulta
(12/08/2009)
ABSTRACT: Thyroid hormones exert a crucial role in brain formation, maturation and functionality. The
deficiency of thyroid hormones in the adult rat induces hippocampal neuronal damage and
also reduces Na+/K+-ATPase ...