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L-Allylglycine dissociates the neural substrates of fear in the periaqueductal gray of rats
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
The dorsal (dPAG) and ventral (vPAG) regions of the periaqueductal gray are well known to contain the neural substrates of fear and anxiety. Chemical or electrical stimulation of the dPAG induces freezing, followed by a ...
Hypothalamic sites responding to predator threats - the role of the dorsal premammillary nucleus in unconditioned and conditioned antipredatory defensive behavior
(WILEY-BLACKWELL, 2008)
In this study we provide a comprehensive analysis of the hypothalamic activation pattern during exposure to a live predator or an environment previously associated with a predator. Our results support the view that ...
Serotonergic modulation in neuropathy induced by oxaliplatin: Effect on the 5HT(2C) receptor
(Elsevier B.V., 2014-07-15)
Fluoxetine has been shown to be effective in clinical and experimental studies of neuropathic pain. Besides to increase serotonin levels in the synaptic cleft, fluoxetine is able to block the serotonergic 5-HT2C receptor ...
The functional role of ascending nociceptive control in defensive behavior
(ElsevierAmsterdam, 2012)
Participação de áreas do tronco encefálico na resposta respiratória ao CO2
(Universidade Federal de São CarlosBRUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, 2013-09-06)
The periaqueductal gray (PAG), a midbrain structure, is directly related to the modulation of survival behaviors and has direct projections to several central nuclei that are involved in breathing control, including the ...
c-FOS and n-NOS reactive neurons in response to circulating Phoneutria nigriventer spider venom
(Pergamon-elsevier Science LtdOxfordInglaterra, 2007)
Motor cortex stimulation inhibits thalamic sensory neurons and enhances activity of PAG neurons: Possible pathways for antinociception
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Motor cortex stimulation is generally suggested as a therapy for patients with chronic and refractory neuropathic pain. However, the mechanisms underlying its analgesic effects are still unknown. In a previous study, we ...