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Role of VDR in 1α,25-dihydroxyvitamin D3-dependent non-genomic activation of MAPKs, Src and Akt in skeletal muscle cells
(Pergamon-Elsevier Science Ltd, 2013-06)
1α,25-dihydroxyvitamin D3 [1,25D] is recognized as a steroid hormone that rapidly elicits intracellular signals in various tissues. In skeletal myoblasts, we have previously demonstrated that one of the 1,25Dinduced ...
Analysis of vitamin D receptor gene (VDR) polymorphisms in Turner syndrome patients
(Informa Healthcare, 2012-04-01)
Individuals with Turner syndrome (TS) have increased risk for autoimmune diseases, especially thyroid abnormalities. the function of the vitamin D receptor (VDR) gene is influenced by several genetic polymorphisms which ...
Mapeamento do receptor de vitamina D (VDR) no complexo prostático deratos Wistar durante o envelhecimento
(Universidade Federal de Minas GeraisUFMG, 2016-02-19)
The prostate is regulated by a complex interplay of endocrine and paracrine signals, including Vitamin D that acts via its specific VDR receptor, carrying out diverse functions such as calcium homeostasis, anti-inflammatory ...
Mapeamento do receptor de vitamina D (VDR) no complexo prostático de ratos Wistar durante o envelhecimento
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2016-02-19)
The prostate is regulated by a complex interplay of endocrine and paracrine signals, including
Vitamin D that acts via its specific VDR receptor, carrying out diverse functions such as
calcium homeostasis, anti-inflammatory ...
VDR activation of intracellular signaling pathways in skeletal muscle
(Elsevier Ireland, 2011-12)
The purpose of this article is to review the activation of signal transduction pathways in skeletal muscle cells by the hormone 1α,25(OH) 2-vitamin D 3 [1α,25(OH) 2D 3], focusing on the role of the vitamin D receptor (VDR). ...
Impact of VDR and RXR expression in non-melanoma skin cancer pathogenesis
(2022-01-01)
1,25(OH)2D3, the active form of vitamin D, has been extensively studied for its putative protective activities against tumors. It does biological work by connecting to a nuclear receptor called VDR, which heterodimerizes ...
Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer
(Wichtig Publishing, 2017)
Introduction: Vitamin D receptor (VDR) and proteins encoded by the genes CYP27B2 and CYP24A1 involved in the production and inactivation of vitamin D can influence vitamin D and the susceptibility to colorectal cancer ...
Actions of 1,25(OH)2-vitamin D3 on the cellular cycle depend on VDR and p38 MAPK in skeletal muscle cells
(BioScientifica, 2014-12)
Previously, we have reported that 1,25(OH)2-vitamin D3 (1,25D) activates p38 MAPK (p38) in a vitamin D receptor (VDR)-dependent manner in proliferative C2C12 myoblast cells. It was also demonstrated that 1,25D promotes ...
Estudo da interação da fisalina F com o receptor da vitamina D
(2010)
As fisalinas são seco-esteróides isolados de espécies do gênero Physalis que apresentam diversas atividades biológicas. Em estudos in vitro e em modelos de doenças mediadas pelo sistema imune, foi demonstrado que a fisalina ...
Role of VDR in 1α,25-dihydroxyvitamin D3-dependent non-genomic activation of MAPKs, Src and Akt in skeletal muscle cells
(Elsevier, 2013-07)
1,25-dihydroxyvitamin D3 [1,25D] is recognized as a steroid hormone that rapidly elicits intracellular signals in various tissues. In skeletal myoblasts, we have previously demonstrated that one of the 1,25Dinduced non-genomic ...