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Adiponectina determinaría el predominio de VLDL alteradas en el síndrome metabólicoAdiponectin would determine the predominance of altered VLDL in metabolic syndromeAdiponectina iria determinar o predomínio de VLDL alteradas na síndrome metabólica
(Federación Bioquímica de la Provincia Buenos Aires, 2016-11)
El objetivo del trabajo fue evaluar si la reducción de adiponectina (ADP) en el síndrome metabólico (SMet), influencia las características aterogénicas de VLDL. Se estudiaron 45 pacientes con SMet y 15 controles sanos. En ...
Hepatic denervation impairs the assembly and secretion of VLDL-TAG
(JOHN WILEY & SONS LTD, 2008)
VLDL secretion is a regulated process that depends on the availability of lipids, apoB and MTP. Our aim was to investigate the effect of liver denervation upon the secretion of VLDL and the expression of proteins involved ...
Role of HDL in neutralizing the VLDL effect on endothelial dysfunction
(Elsevier, 2013-09)
It has been reported that LDL inhibits endothelium-dependent relaxation (EDR) and that HDL can neutralize this effect. However, the atherogenic properties of VLDL have been so far difficult to demonstrate. Studies on VLDL ...
Predominance of large VLDL particles in metabolic syndrome, detected by size exclusion liquid chromatography
(Pergamon-Elsevier Science Ltd, 2012-03)
Objective: To study size heterogeneity of triglyceride rich lipoproteins (TRL) in metabolic syndrome (MS). Design and methods: Thirty MS patients and 14 healthy subjects were included. In fasting serum we measured: lipid ...
Does non-alcoholic fatty liver impair alterations of plasma lipoproteins and associated factors in metabolic syndrome?
(Elsevier Science, 2011-03)
Background: Hepatic steatosis (HS) is closely associated to metabolic syndrome (MS). Both, VLDL-triglyceride oversecretion and intrahepatic deposits, can take place. We evaluated VLDL characteristics, CETP, hepatic lipase ...
Effects of Exercise Training on Hepatic Microsomal Triglyceride Transfer Protein Content in Rats
(GEORG THIEME VERLAG KG, 2009)
Microsomal triglyceride transfer protein (MTP) is a protein that exerts a central regulatory role in very-low-density lipoprotein (VLDL) assembly and secretion. The purpose of the study was to investigate the effects of ...
Supplementation with n-3, n-6, n-9 fatty acids in an insulin-resistance animal model: Does it improve VLDL quality?
(Royal Society of Chemistry, 2017-05)
Insulin-resistance (IR), of increased cardiovascular risk, is characterized by the production of altered VLDL with greater atherogenicity. Dietary fatty acids influence the type of circulating VLDL. But, it is not clear ...
Overproduction of altered VLDL in an insulin-resistance rat model: Influence of SREBP-1c and PPAR-α
(Elsevier Doyma Sl, 2015-07)
Background: In insulin-resistance, VLDL presents alterations that increase its atherogenic potential. The mechanism by which insulin-resistance promotes the production of altered VLDL is still not completely understood. ...
Advances in the knowledge and treatment of dyslipoproteinemiasAvances en el conocimiento y manejo de las dislipoproteinemias
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2003)