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Pilot assessment of vascular endothelial growth factor receptors and trafficking pathways in recurrent and metastatic canine subcutaneous mast cell tumours
(2017-08-01)
Canine subcutaneous mast cell tumour (scMCT) shows less aggressive biological behaviour than cutaneous MCT. Vascular endothelial growth factor receptor 2 (VEGFR2) is expressed by neoplastic cells in canine scMCT, but the ...
Expression and prognostic significance of vascular endothelial growth factor-A (VEGF-A) and its receptor in canine prostate cancer
(2021-10-01)
Background: Vascular endothelial growth factor-A (VEGF-A) and its receptor, VEGF receptor-2 (VEGFR-2), represent a complex family of angiogenic molecules consisting of different ligands and receptors. Due to the importance ...
Lymphangiogenic VEGF-C and VEGFR-3 expression in genetically characterised gastrointestinal stromal tumours
(F Hernandez, 2011-12-01)
This study aimed to assess the distribution of VEGF-C and VEGFR-3 expression in gastrointestinal stromal tumours (GISTs), and to analyse the value of lymphatic vessel density (LVD) in a tumour that is believed to preferentially ...
Inibição do cross-talk entre alfa (v) beta (3) e VEGFR2 na angiogênese pela desintegrina DisBa-01
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2018-05-23)
Angiogenesis, a process by which new capillaries are formed from pre-existing vasculature, is essential in both physiological and pathological conditions. Inadequate balance between pro and antiangiogenic factors can ...
A theoretical analysis of the inhibition of the VEGFR-2 vascular endothelial growth factor and the anti-proliferative activity against the HepG2 hepatocellular carcinoma cell line by a series of 1-(4-((2-oxoindolin-3-ylidene)amino)phenyl)-3-arylureas
(Scholars Research Library, 2016)
An analysis of the relationships between electronic structure and the inhibition of the kinase activity of VEGFR-2 was carried out for a series of 1-(4-((2-oxoindolin-3-ylidene)amino)phenyl)-3-arylureas. A similar study ...
Maternal protein restriction differentially alters the expression of AQP1, AQP9 and VEGFr-2 in the epididymis of rat offspring
(2019-02-01)
Background: Maternal protein restriction causes sperm alterations in the offspring, most of which are associated with epididymal functions. Because fluid reabsorption/secretion dynamics in the epididymal environment play ...
Expresión del factor de crecimiento endotelial vascular (VEGF-A) y de su receptor (VEGFR-2) en la leucemia linfoblástica aguda pediátrica
(2011-06-27)
Acute lymphoblastic leukemia (ALL) is the principal childhood cancer. It represents the
second mortality cause in Mexican childhood between one and 14 years old. Similarly to
solid tumor growth, it haven been suggested ...
Deregulation of VEGFR-2 and PDGFR expression and microvascular density in a triple-negative model of canine malignant mammary tumors with lymph node or lung metastasis
(2019-01-01)
Canine mammary tumors (CMT) represent the most common cancer in noncastrated female dogs. Interestingly, triple-negative tumors are the most common molecular subtype in female dogs. In this study, we proposed to evaluate ...