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Vacuolar targeting and characterization of recombinant antibodies
(Humana Press, 2018-06)
Plant-based platforms are extensively use for the expression of recombinant proteins, including monoclonal antibodies (mAbs). Generally, immunoglobulins (Igs) are sorted to the apoplast, which is often afflicted with intense ...
Two short sequences from amaranth 11S globulin are sufficient to target green fluorescent protein and beta-glucuronidase to vacuoles in Arabidopsis cells
(Elsevier France-editions Scientifiques Medicales Elsevier, 2007-12)
Vacuolar sorting of seed storage proteins is a very complex process since several sorting pathways and interactions among proteins of different classes have been reported. In addition, although the C-terminus of several ...
Vacuolar targeting of recombinant antibodies in Nicotiana benthamiana
(Wiley Blackwell Publishing, Inc, 2016-12)
Plant-based platforms are extensively used for the expression of recombinant proteins, including monoclonal antibodies. However, to harness the approach effectively and leverage it to its full potential, a better understanding ...
Vacuolar deposition of recombinant proteins in plant vegetative organs as a strategy to increase yields
(Taylor, 2017-05)
Delivery of recombinant proteins to vegetative tissue vacuoles was considered inconvenient since this compartment was expected to be hydrolytic; nevertheless there is growing evidence that certain foreign proteins accumulate ...
Heterologous Expression of Syntaxin 6 in Saccharomyces cerevisiae
(Sociedad de Biología de Chile, 2002)
The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles
(BirkhauserBasel, 2013-09-01)
The co-chaperone stress-inducible protein 1 (STI1) is released by astrocytes, and has important neurotrophic properties upon binding to prion protein (PrPC). However, STI1 lacks a signal peptide and pharmacological approaches ...