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Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter Polymorphisms among distinct ethnic groups from Brazil

Fertrin, KY; Goncalves, MS; Saad, STO; Costa, FF (Wiley-lissNew YorkEUA, 2002)

Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter polymorphisms among distinct ethnic groups from Brazil

Fertrin, Kleber Yotsumoto; Gonçalves, Marilda de Souza; Saad, Sara Teresinha Olalla; Costa, Fernando Ferreira (Wiley, 2002)

Binding of the substrate UDPglucuronic acid induces conformational changes in the xanthan gum glucuronosyltransferase

Salinas, Sergio R.; Petruk, Ariel Alcides; Brukman, Nicolás Gastón; Bianco, Maria Isabel; Jacobs, Melisa; Marti, Marcelo Adrian; Ielpi, Luis (Oxford University Press, 2016-06)

GumK is a membrane-associated glucuronosyltransferase of Xanthomonas campestris that is involved in xanthan gum biosynthesis. GumK belongs to the inverting GT-B superfamily and catalyzes the transfer of a glucuronic acid ...

Clinical and genetic risk factors for moderate hyperbilirubinemia in Brazilian newborn infants

Mezzacappa, MA; Facchini, FP; Pinto, AC; Cassone, AEL; Souza, DS; Bezerra, MAC; Albuquerque, DM; Saad, STO; Costa, FF (Nature Publishing GroupNew YorkEUA, 2010)

Udp-glucuronosyltransferase 1 Gene Promoter Polymorphism Is Associated With Increased Serum Bilirubin Levels And Cholecystectomy In Patients With Sickle Cell Anemia [1]

Fertrin K.Y.; Melo M.B.; Assis A.M.; Saad S.T.O.; Costa F.F. (, 2003)

Tacrolimus (Tacro) strongly inhibits intestinal UDP-glucuronosyltransferase (UGT) 1A8

Yu, Jian; Wang, Chuan-Qiang; Fang, Long-Hao; Li, Meng; Wang, Xiangyang; Dai, Lu-Lu; Gao, Ya-Jie (2012)

Levothyroxine Exhibits Inhibitory Effect towards UDP-Glucuronosyltransferase (UGT) 1A6-Mediated 4-Methylumbelliferone (4-MU) Glucuronidation

Wang, Chuan-Qiang; Song, Ming-Zhu; Zhu, Hou-Wei; Yi, Jia-Jun; Luan, Ming-Chun; Shi, Ai-Yuan; Qu, Yan-Qing (2012)

Strong Inhibition of UDP-Glucuronosyltransferase (UGT) 1A1 by Levothyroxine Indicates the Potential UGT-Inhibition Based Adverse Effect of Levothyroxine

Zhao, Hua-Dong; Bao, Guo-Qiang; He, Xian-Li; Wu, Tao; Wang, Cheng-Guo; Wang, Sheng-Zhi; Zang, Li; Lu, Jian-Guo; Du, Xi-Lin (2012)

Melatonin protects the cytochrome P450 system through a novel antioxidant mechanism

Eugenia Letelier, Maria; Jara Sandoval, Jose; Molina Berrios, Alfredo; Faundez, Mario; Aracena Parks, Paula; Aguilera, Felipe (ELSEVIER IRELAND LTD, 2010)

Melatonin, an endogenous hormone, is used as an antioxidant drug in doses quite higher than the endogenous circulating levels of this hormone. Hepatic endoplasmic reticulum contains the cytochrome P450 (CYP450) system, ...

Drug Metabolism Synthetic (Phase II) Reactions

Talevi, Alan; Bellera, Carolina Leticia (Springer Nature Switzerland AG, 2021)

In synthetic (or Phase II or conjugation) reactions, an endogenous or exogenous compound (the substrate of the reaction) is coupled to an endogenous conjugating moiety (sometimes called endocon). The conjugating moiety is ...