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Estudo comparativo das toxinas PnTx2-5 e PnTx2-6 sobre canais de sódio
(Universidade Federal de Minas GeraisUFMG, 2004-01-14)
The spider Phoneutria nigriventer is the major responsible for the araneism accidents in the Southeast of Brazil. The predominant symptoms of the envenomation indicate a general hyperexcitability. Two toxins of the venom, ...
Clonagem e expressão da toxina TX3-1 do veneno da aranha phneutria nigriventer
(Universidade Federal de Minas GeraisUFMG, 2008-05-28)
The toxin Tx3-1 purified from the spider venom Phoneutria nigriventer is a blocker of potassium channels with great pharmacological potential. However the purification of the toxin from Phoneutria nigriventer crude venom ...
Expressão heteróloga de neurotoxinas do veneno da aranha Phoneutrianigriventer
(Universidade Federal de Minas GeraisUFMG, 2011-06-17)
The venom of the spider Phoneutria nigriventer contains several peptides that act on ion channels and receptors of the nervous system of insects and mammals. The toxins Tx3-6 and Tx3-4 are voltage-gated calcium channel ...
Estudios básicos para iniciar la producción de cultivares de tomate Solanum Lycopersicum L. con resistencia al pasador del fruto Neoleucinodes elegantalis (Guenée)
(2007)
Se hicieron cruzamientos interespecíficos entre tomate S. lycopersicum variedad Unapal Maravilla (♀) y trece accesiones silvestres de Solanum sección Lycopersicum (♂). El primer retrocruzamiento (RC1) se realizó entre ...
Antibacterial activity of the non-cytotoxic peptide (p-BthTX-I)2 and its serum degradation product against multidrug-resistant bacteria
(2017-11-01)
Antimicrobial peptides can be used systemically, however, their susceptibility to proteases is a major obstacle in peptide-based therapeutic development. In the present study, the serum stability of p-BthTX-I (KKYRYHLKPFCKK) ...
How independent are the appearances of n-mers in different genomes?
(2004)
Motivation: Analysis of statistical properties of DNA sequences is important for evolutional biology as well as for DNA probe and PCR technologies. These technologies, in turn, can be used for organism identification, which ...
How independent are the appearances of n-mers in different genomes?
(2004)
Motivation: Analysis of statistical properties of DNA sequences is important for evolutional biology as well as for DNA probe and PCR technologies. These technologies, in turn, can be used for organism identification, which ...
Effect of C-terminal and N-terminal dimerization and alanine scanning on antibacterial activity of the analogs of the peptide p-BthTX-I
(2022-03-01)
The peptide (p-BthTX-I)2 [(KKYRYHLKPFCKK)2] and its analog des-Lys12,Lys13-(p-BthTX-I)2 [(KKYRYHLKPFC)2] showed activity against bacteria and potential specificity against prokaryotic cells. In this study, we synthesized ...
Efeito da toxina PhTx3-4 do veneno de Phoneutria nigriventer nos níveis de Ca2+ intracelular na exocirose em sinaptosomas
(Universidade Federal de Minas GeraisUFMG, 2007-09-20)
Calcium influx and synaptic vesicle exocytosis at nerve terminals are key events in the neurotransmission. Calcium entrance throughout voltage-gated calcium channels in response to a depolarizing stimulus is the main signal ...