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Immunohistochemical evaluation of prostaglandin E2 and vascular endothelial growth factor in canine cutaneous mast cell tumours
(Wiley-Blackwell Publishing, Inc, 2010-03-01)
Vascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE-2) appear to play a critical role in tumour neovascularization. In this study, we have investigated the expression of VEGF and PGE-2 in 53 canine cutaneous ...
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy
(2010-05-13)
Abstract
Background
Phagocytosis of apoptotic cells by macrophages induces a suppressor phenotype. Previous data from our group suggested that this occurs via Platelet-activating ...
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy
(2010-05-13)
Abstract
Background
Phagocytosis of apoptotic cells by macrophages induces a suppressor phenotype. Previous data from our group suggested that this occurs via Platelet-activating ...
A mathematical model of chemotherapy response to tumour growth
(2011)
A simple mathematical model, developed to simulate the chemotherapy response to tumour growth with stabilized vascularization, is presented as a system of three differential equations associated with the normal cells, ...
A mathematical model of chemotherapy response to tumour growth
(2011-12-01)
A simple mathematical model, developed to simulate the chemotherapy response to tumour growth with stabilized vascularization, is presented as a system of three differential equations associated with the normal cells, ...
T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour
(Blackwell Publishing, 2013)
T helper type 17 (Th17) lymphocytes are found in high frequency in
tumour-burdened animals and cancer patients. These lymphocytes, characterized
by the production of interleukin-17 and other pro-inflammatory
cytokines, ...
Immunohistochemical evaluation of prostaglandin E2 and vascular endothelial growth factor in canine cutaneous mast cell tumours
(Wiley-Blackwell Publishing, Inc, 2010-03-01)
Vascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE-2) appear to play a critical role in tumour neovascularization. In this study, we have investigated the expression of VEGF and PGE-2 in 53 canine cutaneous ...
Does the tumour microenvironment alter tumorigenesis and clinical response in transmissible venereal tumour in dogs?
(2018-09-01)
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread naturally between dogs, with the ability to develop and evade the immune system, despite strict immune surveillance of the host. ...
Involvement of formyl peptide receptors in the stimulatory effect of crotoxin on macrophages co-cultivated with tumour cells
(Pergamon PressOxford, 2013-11)
Crotoxin (CTX) is the main neurotoxic component of Crotalus durissus terrificus snake venom. It inhibits tumour growth and modulates the function of macrophages, which are essential cells in the tumour microenvironment. ...
Spatial modelling of tumour drug resistance: the case of GIST liver metastases
(Oxford university press, 2017)
This work is devoted to modelling gastrointestinal stromal tumour metastases to the liver, their growth and resistance to therapies. More precisely, resistance to two standard treatments based on tyrosine kinase inhibitors ...