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Curcumin requires tumor necrosis Factor α signaling to alleviate cognitive impairment elicited by Lipopolysaccharide
(KargerBasel, 2013)
A decline in cognitive ability is a typical feature of the normal aging process, and of neurodegenerative disorders such as Alzheimer’s, Parkinson’s and Huntington’s diseases. Although their etiologies differ, all of these ...
Periapical lesions decrease insulin signal and cause insulin resistance
(2013-05-01)
Introduction: Inflammatory cytokines are associated with decreased insulin signal transduction. Moreover, local oral inflammation, such as that accompanying periodontal disease, is associated with insulin resistance and ...
Tumor necrosis factor-α-stimulated membrane type 1-matrix metalloproteinase production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts
(2009)
Background and Objectives: Membrane type 1-matrix metalloproteinase (MT1-MMP) is a collagenolytic enzyme involved in connective tissue remodeling. In periodontal tissues, either cytokines or growth factors regulate the ...
Periapical lesions decrease insulin signal and cause insulin resistance
(2013-05-01)
Introduction: Inflammatory cytokines are associated with decreased insulin signal transduction. Moreover, local oral inflammation, such as that accompanying periodontal disease, is associated with insulin resistance and ...
Triclosan inhibits tumor necrosis factor-α-stimulated urokinase production in human gingival fibroblasts
(2009)
Background and Objectives: Destruction of the supporting periodontal tissues is
mediated by the action of several proteolytic enzymes. Urokinase is a serine
protease that plays a key role in connective tissue destruction ...
Up-regulation of tumor necrosis factor-α pathway survival genes and of the receptor TNFR2 in gastric cancer
(2019-04-01)
BACKGROUND Gastric carcinogenesis can be induced by chronic inflammation triggered by Helicobacter pylori (H. pylori) infection. Tumor necrosis factor (TNF)-α and its receptors (TNFR1 and TNFR2) regulate important cellular ...
Silibinin attenuates oxidative metabolism and cytokine production by monocytes from preeclamptic women.
(2013-04-01)
Silibinin is a polyphenolic plant flavonoid with anti-inflammatory properties. The present study investigated the effect of silibinin on oxidative metabolism and cytokine production - tumor necrosis factor-alpha (TNF-α), ...
Silibinin attenuates oxidative metabolism and cytokine production by monocytes from preeclamptic women.
(2013-04-01)
Silibinin is a polyphenolic plant flavonoid with anti-inflammatory properties. The present study investigated the effect of silibinin on oxidative metabolism and cytokine production - tumor necrosis factor-alpha (TNF-α), ...
Maternal periodontal disease in rats decreases insulin sensitivity and insulin signaling in adult offspring
(2013-03-01)
Background: Periodontal disease during pregnancy has been recognized as one of the causes of preterm and lowbirth- weight (PLBW) babies. Several studies have demonstrated that PLBW babies are prone to developing insulin ...