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Trypomastigotes and amastigotes of Trypanosoma cruzi induce apoptosis and STAT3 activation in cardiomyocytes in vitro.

Stahl, Philipp; Ruppert, Volker; Meyer, Thomas; Schmidt, Jorg; Campos, Marco Antonio; Gazzinelli, Ricardo Tostes; Maisch, Bernhard; Schwarz, Ralph T.; Debierre-Grockiego, Francoise (Springer, 2018)

Effects of Nifurtimox and benznidazole upon glutathione and trypanothione content in epimastigote, trypomastigote and amastigote forms of Trypanosoma cruzi

Maya Arango, Juan; Repetto Scaramelli, Yolanda; Agosín, Moisés; Ojeda, José Manuel; Tellez, Rowena; Gaule, Carlos; Morello Casté, Antonio (1997)

Uptake of Host Cell Transforming Growth Factor- by Trypanosoma cruzi Amastigotes in Cardiomyocytes Potential Role in Parasite Cycle Completion

Waghabi, Mariana C.; Keramidas, Michelle; Baily, Sabine; Degrave, Wim M.; LIma, Leila Mendonça; Soeiro, Maria Nazaré C.; Meirelles, Maria de Nazareth L.; Paciornik, Sidney; Araujo-Jorge, Tania C.; Feige, Jean-Jacques (American Society for Investigative Pathology, 2020)

Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles

Sanchez, G; Cuellar, D; Zulantay, I; Gajardo, M; Gonzalez Martin, G (SOCIEDAD BIOLGIA CHILE, 2002)

The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease. Ethylcyanoacrylate ...

Involvement of host cell heparan sulfate proteoglycan in Trypanosoma cruzi amastigote attachment and invasion

Medeiros, R. Bambino; Oliveira, F. O. R.; Calvet, C. M.; Vicente, D.; Toma, L.; Krieger, M. A.; Meirelles, M. N.; Pereira, M. C. S. (Cambridge University Press, 2018)

Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi

Bonfim-Melo, Alexis [UNIFESP]; Ferreira, Eden R. [UNIFESP]; Mortara, Renato A. [UNIFESP] (Frontiers Media Sa, 2018)

This study evaluated the participation of host cell Rho-family GTPases and their effector proteins in the actin-dependent invasion by Trypanosoma cruzi extracellular amastigotes (EAs). We observed that all proteins were ...

Trypanosoma cruzi: amastigote polymorphism defined by monoclonal antibodies

Verbisck, Newton Valério [UNIFESP]; Da-Silva, S. [UNIFESP]; Mortara, Renato Arruda [UNIFESP] (Associação Brasileira de Divulgação Científica, 1998-12-01)

We have raised monoclonal antibodies (mAbs) directed towards amastigote forms of Trypanosoma cruzi, and shown that mAbs 1D9 and 4B9 are carbohydrate while mAb 4B5 activity is resistant to periodate oxidation of the antigen. ...

Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi

Garzoni, Luciana R.; Caldera, Aura; Meirelles, Maria de Nazareth L.; Castro, Solange L. de; Docampo, Roberto; Meints, Gary A.; Oldfield, Eric; Urbina, Julio A. (Elsevier, 2020)

Mechanism of action of a Nitroimidazole-Thiadiazole derivate upon Trypanosoma cruzi tissue culture amastigotes

Castro, Solange L. de; Meirelles, Maria de Nazareth L. de (Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)

Trypanosoma cruzi: Effect of protein kinase inhibitors and cytoskeletal protein organization and expression on host cell invasion by amastigotes and metacyclic trypomastigotes

Procopio, D. O.; Silva, S. da; Cunningham, C. C.; Mortara, R. A. (Academic Press Inc, 1998-09-01)

Although trypomastigotes are regarded as the classic infective forms of T. cruzi, amastigotes generated extracellularly or released from infected cells during lysis may circulate and infect other cells. We have compared ...

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