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Notes on syphilis vaccine development
(Frontiers Media, 2022)
The quest for a syphilis vaccine to provide protection from infection or disease began not long after the isolation of the first Treponema pallidum subspecies pallidum (T. pallidum) strain in 1912. Yet, a practical and ...
Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: Study protocol
(BioMed Central, 2020)
Background: The syphilis epidemic continues to cause substantial morbidity and mortality worldwide, particularly in low- and middle-income countries, despite several recent disease control initiatives. Though our understanding ...
Performance of Treponema pallidum recombinant proteins in the serological diagnosis of syphilis
(Public Library of Science, 2020)
Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru
(Wolters Kluwer Health, 2016)
We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru. ...
Cytokine expression in Treponema pallidum infection
(BioMed Central, 2019)
Background. Current syphilis tests cannot distinguish between active and past syphilis among patients with serofast rapid plasma reagin (RPR) titers. We investigated whether cytokine profiles might provide insight in the ...
Laboratory Evaluation of a Smartphone-Based Electronic Reader of Rapid Dual Point-of-Care Tests for Antibodies to Human Immunodeficiency Virus and Treponema pallidum Infections
(BMJ Publishing Group, 2017)
BACKGROUND: Dual point-of-care tests for antibodies to human immunodeficiency virus (HIV) and Treponema pallidum allow for same-day testing and treatment and have been demonstrated to be cost-effective in preventing the ...
Prevalence of HIV, hepatitis B virus and treponema pallidum in inmates in the preventive detention Center of Arica, Chile Prevalencia del virus de la inmunodeficiencia humana, virus de la hepatitis B y treponema pallidum en reclusos del centro de detenció
(Sociedad Chilena de Infectologia, 2017)
© 2018, Sociedad Chilena de Infectologia. All rights reserved. Background: The risk groups for sexual transmitted diseases (STDs) are sex workers, drug addicts, young people in early sexual initiation, and population in ...