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Trypanosoma cruzi: establishment of permeable cells for RNA processing analysis with drugs
(Instituto Oswaldo Cruz, Ministério da Saúde, 2004-10-01)
Pre-mRNA maturation in trypanosomatids occurs through a process called trans-splicing which involves excision of introns and union of exons in two independent transcripts. For the first time, we present the standardization ...
Trypanosoma cruzi: establishment of permeable cells for RNA processing analysis with drugs
(Instituto Oswaldo Cruz, Ministério da Saúde, 2004-10-01)
Pre-mRNA maturation in trypanosomatids occurs through a process called trans-splicing which involves excision of introns and union of exons in two independent transcripts. For the first time, we present the standardization ...
Trypanosoma cruzi: establishment of permeable cells for RNA processing analysis with drugs
(Instituto Oswaldo Cruz, Ministério da Saúde, 2014)
Reação de trans-splicing in vitro utilizando extrato nuclear livre de células e sequencia parcial de alfa tubulina de Trypanosoma cruzi
(Universidade Estadual Paulista (UNESP), 2014)
Reação de trans-splicing in vitro utilizando extrato nuclear livre de células e sequencia parcial de alfa tubulina de Trypanosoma cruzi
(Universidade Estadual Paulista (Unesp), 2011-12-08)
A família Trypanosomatidae compreende um grande número de protozoários parasitas, incluindo importantes agentes etiológicos de doenças humanas. Entre os causadores de doenças, destaca-se o Trypanosoma brucei (responsável ...
Reação de trans-splicing in vitro utilizando extrato nuclear livre de células e sequencia parcial de alfa tubulina de Trypanosoma cruzi
(Universidade Estadual Paulista (Unesp), 2011-12-08)
A família Trypanosomatidae compreende um grande número de protozoários parasitas, incluindo importantes agentes etiológicos de doenças humanas. Entre os causadores de doenças, destaca-se o Trypanosoma brucei (responsável ...
Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing
(Oxford University Press, 2013-07)
Abnormal metabolism of the tau protein is central to the pathogenesis of a number of dementias, including Alzheimer's disease. Aberrant alternative splicing of exon 10 in the tau pre-mRNA resulting in an imbalance of tau ...
Marchantia polymorpha mitochondrial orf identifies transcribed sequence in angiosperm mitochondrial genome
(Elsevier Science BvAmsterdamHolanda, 2001)
Insights into the Regulation of mRNA Processing of Polycistronic Transcripts Mediated by DRBD4/PTB2, a Trypanosome Homolog of the Polypyrimidine Tract‐Binding Protein
(Blackwell Publishing, 2016-07)
Trypanosomes regulate gene expression mostly by posttranscriptional mechanisms, including control of mRNA turnover and translation efficiency. This regulation is carried out via certain elements located at the 3'-untranslated ...
Modulación de isoformas de la proteína asociada a microtúbulos TAU: rescate de fenotipos moleculares y funcionales en un modelo murino de taupatíaModulation of microtubule associated protein tau isoforms: rescue of functional and molecular phenotypes in a mouse model of tauopathy
(2019-03-07)
Las enfermedades neurodegenerativas pueden ser causadas por una miríada de factores que conllevan a la muerte y/o disfunción de determinadas neuronas del cerebro humano. La enfermedad de Alzheimer (EA) y otras demencias ...