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Natural variation of the cardiac transcriptome in humans
(Taylor & Francis, 2021)
TRAP-SEQ of eukaryotic translatomes applied to the detection of polysome-associated long noncoding RNAs
(Springer, 2020)
Translating ribosome affinity purification (TRAP) technology allows the isolation of polysomal complexes and the RNAs associated with at least one 80S ribosome. TRAP consists of the stabilization and affinity purification ...
Extensive translational regulation through the proliferative transition of Trypanosoma cruzi revealed by Multi-Omics
(American Society for Microbiology, 2021)
Trypanosoma cruzi is the etiological agent for Chagas disease, a neglected parasitic disease in Latin America. Gene transcription control governs the eukaryotic cell replication but is absent in trypanosomatids; thus, it ...
Translational switching from growth to defense – a common role for TOR in plant and mammalian immunity?
(Oxford University Press, 2017-04)
Characterization of mRNA populations associatedwith the translational machinery (translatome)is shedding light on the molecular mechanisms ofplant environmental responses. The work presentedby Meteignier et al. (2017) ...
PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses
(RNA Society, 2020)
Programmed Cell Death 4 (PDCD4) protein is a tumour suppressor that inhibits translation through the mTOR dependent initiation factor EIF4A, but its functional role and mRNA targets in neurons remain largely unknown. Our ...
Nuclear compartmentalization contributes to stage-specific gene expression control in Trypanosoma cruzi
(Frontiers Media, 2017)
In the protozoan parasite Trypanosoma cruzi, as in other trypanosomatids, transcription of protein coding genes occurs in a constitutive fashion, producing large polycistronic transcription units. These units are composed ...
Microproteins in skeletal muscle: hidden keys in muscle physiology
(Wiley Open Access, 2021)